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加拿大初级保健患者的多种合并症与血压控制。

Multimorbidity and Blood Pressure Control in Patients Attending Primary Care in Canada.

机构信息

University of Sydney, Sydney, NSW, Australia.

University of Toronto, Toronto, ON, Canada.

出版信息

J Prim Care Community Health. 2023 Jan-Dec;14:21501319231215025. doi: 10.1177/21501319231215025.

Abstract

BACKGROUND

There has been conflicting evidence on the association between multimorbidity and blood pressure (BP) control. This study aimed to investigate this associations in people with hypertension attending primary care in Canada, and to assess whether individual long-term conditions are associated with BP control.

METHODS

This was a cross-sectional study in people with hypertension attending primary care in Toronto between January 1, 2017 and December 31, 2019. Uncontrolled BP was defined as systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg. A list of 11 a priori selected chronic conditions was used to define multimorbidity. Multimorbidity was defined as having ≥1 long-term condition in addition to hypertension. Logistic regression models were used to estimate the association between multimorbidity (or individual long-term conditions) with uncontrolled BP.

RESULTS

A total of 67 385 patients with hypertension were included. They had a mean age of 70, 53.1% were female, 80.6% had multimorbidity, and 35.7% had uncontrolled BP. Patients with multimorbidity had lower odds of uncontrolled BP than those without multimorbidity (adjusted OR = 0.72, 95% CI 0.68-0.76). Among the long-term conditions, diabetes (aOR = 0.73, 95%CI 0.70-0.77), heart failure (aOR = 0.81, 95%CI 0.73-0.91), ischemic heart disease (aOR = 0.74, 95%CI 0.69-0.79), schizophrenia (aOR = 0.79, 95%CI 0.65-0.97), depression/anxiety (aOR = 0.91, 95%CI 0.86-0.95), dementia (aOR = 0.87, 95%CI 0.80-0.95), and osteoarthritis (aOR = 0.89, 95%CI 0.85-0.93) were associated with a lower likelihood of uncontrolled BP.

CONCLUSION

We found that multimorbidity was associated with better BP control. Several conditions were associated with better control, including diabetes, heart failure, ischemic heart disease, schizophrenia, depression/anxiety, dementia, and osteoarthritis.

摘要

背景

关于多种合并症与血压(BP)控制之间的关联,一直存在相互矛盾的证据。本研究旨在调查加拿大初级保健机构中高血压患者的这种关联,并评估个体长期疾病是否与 BP 控制相关。

方法

这是一项在 2017 年 1 月 1 日至 2019 年 12 月 31 日期间在多伦多接受初级保健的高血压患者中进行的横断面研究。未控制的 BP 定义为收缩压≥140mmHg 或舒张压≥90mmHg。使用预先选定的 11 种慢性疾病列表来定义多种合并症。多种合并症定义为除高血压外还患有≥1 种长期疾病。使用逻辑回归模型来估计多种合并症(或个体长期疾病)与未控制 BP 之间的关联。

结果

共纳入 67385 例高血压患者。他们的平均年龄为 70 岁,53.1%为女性,80.6%患有多种合并症,35.7%的患者 BP 未得到控制。与无多种合并症的患者相比,患有多种合并症的患者未控制 BP 的可能性较低(校正比值比(OR)=0.72,95%置信区间 0.68-0.76)。在长期疾病中,糖尿病(OR=0.73,95%置信区间 0.70-0.77)、心力衰竭(OR=0.81,95%置信区间 0.73-0.91)、缺血性心脏病(OR=0.74,95%置信区间 0.69-0.79)、精神分裂症(OR=0.79,95%置信区间 0.65-0.97)、抑郁/焦虑(OR=0.91,95%置信区间 0.86-0.95)、痴呆(OR=0.87,95%置信区间 0.80-0.95)和骨关节炎(OR=0.89,95%置信区间 0.85-0.93)与未控制 BP 的可能性较低相关。

结论

我们发现多种合并症与更好的 BP 控制相关。一些疾病与更好的控制相关,包括糖尿病、心力衰竭、缺血性心脏病、精神分裂症、抑郁/焦虑、痴呆和骨关节炎。

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