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一例巨大原发性先天性中胚叶肾瘤经开放性全肾切除术成功治疗:病例报告

A massive primary congenital mesoblastic nephroma was successfully managed through open total nephrectomy: a case report.

作者信息

Samha Raghad, Mansour Marah, AlAwad Yara, Almaalouli Bsher, Mayhoob Reema, Al Sabbagh Aliaa, Aljundi Rama, Barakat Ali

机构信息

Faculty of Medicine, AlBaath University, Homs.

Faculty of Medicine, Tartous University.

出版信息

Ann Med Surg (Lond). 2023 Oct 11;85(12):6159-6163. doi: 10.1097/MS9.0000000000001364. eCollection 2023 Dec.

DOI:10.1097/MS9.0000000000001364
PMID:38098567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10718342/
Abstract

BACKGROUND

Congenital mesoblastic nephroma is the most common renal tumor in children under the age of 6 months, comprising 3-10% of all kidney tumors in children. It is a rare and mostly benign tumor. It divides into cellular, classic, and mixed subtypes. It is typically detected in the third trimester of pregnancy using ultrasonography and magnetic resonance imaging. The best treatment is surgically by completely removing the tumor.

CASE PRESENTATION

We reported a case of a one-day-old female who was born at 31 weeks gestation weighing 1670 g. Preterm labor was due to polyhydramnios, which was diagnosed predelivery. A large mass was detected in the left hypochondrium using computerized tomography, total nephrectomy was performed, and the histopathological examination of the specimen confirmed the diagnosis of congenital mesoblastic nephroma.

CLINICAL DISCUSSION AND CONCLUSION

Early polyhydramnios could be the most significant sign of renal tumors in infants, especially congenital mesoblastic nephroma.

摘要

背景

先天性中胚层肾瘤是6个月以下儿童最常见的肾肿瘤,占儿童所有肾肿瘤的3% - 10%。它是一种罕见且大多为良性的肿瘤。分为细胞型、经典型和混合型亚型。通常在妊娠晚期通过超声和磁共振成像检测到。最佳治疗方法是手术完全切除肿瘤。

病例报告

我们报告了一例1日龄女性,孕31周出生,体重1670克。早产是由于羊水过多,产前已诊断。通过计算机断层扫描在左季肋部检测到一个大肿块,进行了全肾切除术,标本的组织病理学检查证实了先天性中胚层肾瘤的诊断。

临床讨论与结论

早期羊水过多可能是婴儿肾肿瘤尤其是先天性中胚层肾瘤的最重要体征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/782a04ed7dd7/ms9-85-6159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/712fc5e36902/ms9-85-6159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/da62bc7f383f/ms9-85-6159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/782a04ed7dd7/ms9-85-6159-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/712fc5e36902/ms9-85-6159-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/da62bc7f383f/ms9-85-6159-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a257/10718342/782a04ed7dd7/ms9-85-6159-g003.jpg

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本文引用的文献

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Report and follow-up on two new patients with congenital mesoblastic nephroma.报告并随访 2 例先天性中胚层肾瘤新病例。
Ital J Pediatr. 2023 Sep 19;49(1):124. doi: 10.1186/s13052-023-01523-7.
2
Prenatal diagnosis and postnatal management of congenital mesoblastic nephroma: A case report and literature review.先天性中胚层肾瘤的产前诊断与产后管理:一例病例报告及文献综述
Front Pediatr. 2022 Nov 21;10:1040304. doi: 10.3389/fped.2022.1040304. eCollection 2022.
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Prenatal Course and Sonographic Features of Congenital Mesoblastic Nephroma.
先天性中胚层肾瘤的产前病程及超声特征
Diagnostics (Basel). 2022 Aug 12;12(8):1951. doi: 10.3390/diagnostics12081951.
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Prenatal Diagnosis of Fetal Congenital Mesoblastic Nephroma and Neonatal Follow-up.
J Med Ultrasound. 2020 Oct 1;29(2):126-128. doi: 10.4103/JMU.JMU_79_20. eCollection 2021 Apr-Jun.
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Prenatal diagnosis of fetal congenital mesoblastic nephroma by ultrasonography combined with MR imaging: A case report and literature review.超声联合磁共振成像对胎儿先天性中胚层肾瘤的产前诊断:病例报告及文献复习。
Medicine (Baltimore). 2021 Jan 22;100(3):e24034. doi: 10.1097/MD.0000000000024034.
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Congenital mesoblastic nephroma: a single-centre series.先天性中胚层肾瘤:单中心病例系列
Ann R Coll Surg Engl. 2020 Jan;102(1):67-70. doi: 10.1308/rcsann.2019.0111. Epub 2019 Sep 11.
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Prenatal diagnosis of congenital mesoblastic nephroma: a case with poor prognosis.先天性中胚叶肾瘤的产前诊断:一例预后不良的病例
BMJ Case Rep. 2019 Aug 28;12(8):e230297. doi: 10.1136/bcr-2019-230297.
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Congenital Mesoblastic Nephroma Presenting with Hematuria in a Neonate.新生儿先天性中胚层肾瘤伴血尿
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