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先天性中胚层肾瘤:一例产前诊断病例报告

The congenital mesoblastic nephroma: a case report of prenatal diagnosis.

作者信息

Haddad B, Haziza J, Touboul C, Abdellilah M, Uzan S, Paniel B J

机构信息

Department of Obstetrics and Gynecology, CHI Créteil, France.

出版信息

Fetal Diagn Ther. 1996 Jan-Feb;11(1):61-6. doi: 10.1159/000264281.

Abstract

The congenital mesoblastic nephroma is a very rare benign congenital renal tumor. It is the most common renal tumor before the age of 6 months (50%) and it constitutes only 5% of renal tumors before 15 years. The authors report a case of prenatal diagnosis of congenital mesoblastic nephroma revealed by an acute polyhydramnios at 33 weeks of pregnancy. After a preterm labor, the patient delivered at 35 weeks. The newborn underwent a radical nephrectomy. No recurrence was noticed at 10 months. This case of prenatal diagnosis is compared to the 12 cases previously reported. The prognosis of CMN depends on histologic findings, but also on the severity of prematurity induced by the polyhydramnios. The main treatment of this pathology if diagnosed during pregnancy remains the prevention of preterm labor, and after birth the removal of the kidney.

摘要

先天性中胚叶肾瘤是一种非常罕见的良性先天性肾肿瘤。它是6个月前最常见的肾肿瘤(占50%),在15岁前仅占肾肿瘤的5%。作者报告了一例先天性中胚叶肾瘤的产前诊断病例,该病例在妊娠33周时因急性羊水过多而被发现。经过早产,患者在35周时分娩。新生儿接受了根治性肾切除术。10个月时未发现复发。该产前诊断病例与之前报道的12例病例进行了比较。先天性中胚叶肾瘤的预后取决于组织学检查结果,也取决于羊水过多引起的早产严重程度。如果在孕期诊断出这种疾病,主要治疗方法是预防早产,出生后则是切除肾脏。

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