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[动物行为中的抑制模型]

[Models of inhibition in animal behavior].

作者信息

Soubrie P, Chermat R, Poncelet M, Simon P

出版信息

Encephale. 1978;4(5 Suppl):503-11.

PMID:38103
Abstract

The concept of inhibition in psychopharmacology is discussed by presenting different models of behavioral inhibition in animals. The inhibitions induced by fear or anxiety appear as a result of punishment introduction into an unknown situation, frustration... These inhibitions are particularly sensitive to minor tranquilizers. The inhibitions induced by "fatigue" appear when avoidance situations continue for 24 hours or when a situation demands a marked increase of animal activity to obtain the same reward (food). These inhibitions are particularly sensitive to psychoanaleptics. The inhibition induced by placing a animal in an inescapable situation is particularly sensitive to antidepressants.

摘要

通过展示动物行为抑制的不同模型来讨论精神药理学中的抑制概念。恐惧或焦虑引发的抑制是由于在未知情境中引入惩罚、挫折等而产生的……这些抑制对小剂量镇静剂特别敏感。当回避情境持续24小时或当一种情境要求动物活动显著增加以获得相同奖励(食物)时,“疲劳”引发的抑制就会出现。这些抑制对精神兴奋剂特别敏感。将动物置于无法逃避的情境中引发的抑制对抗抑郁药特别敏感。

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