Blombery P A, Ferguson I A, Rosengarten D S, Stuchbery K E, Miles C R, Black A J, Pitt A, Anderson S T, Harper R W, Federman J
Surgery. 1987 Feb;101(2):150-5.
Coronary artery disease (CAD) is a major cause of morbidity and mortality after elective surgical repair of abdominal aortic aneurysm (AAA). The aim of this study was to determine the relationship between the extent of CAD observed in coronary angiograms (more than 50% stenosis) and the frequency of postoperative myocardial ischemic complications in a consecutive series of 84 patients who underwent elective AAA repair. Ninety-four percent of the patients with clinical evidence of CAD had significant disease as observed in coronary angiograms and eight patients had left main CAD. Seventy-two patients underwent AAA repair with a mortality rate of 1.4%; five patients had preliminary myocardial revascularization, and AAA surgery was not recommended for four patients because of severe cardiac disease. Postoperative myocardial ischemic complications occurred in 13.4% of the patients who had undergone surgery--almost exclusively in patients with clinical evidence of CAD. Both myocardial ischemia and preoperative intervention were more frequent in patients with double- or triple-vessel disease than in patients with less extensive disease. Patients with symptoms and with double- or triple-vessel CAD have a high risk of developing myocardial ischemia after AAA surgery. Preliminary myocardial revascularization may be beneficial in this group of patients.
冠状动脉疾病(CAD)是腹主动脉瘤(AAA)择期手术修复后发病和死亡的主要原因。本研究的目的是确定在84例接受择期AAA修复的连续患者系列中,冠状动脉造影中观察到的CAD程度(狭窄超过50%)与术后心肌缺血并发症发生率之间的关系。有CAD临床证据的患者中,94%在冠状动脉造影中显示有明显病变,8例患者有左主干CAD。72例患者接受了AAA修复,死亡率为1.4%;5例患者进行了初步心肌血运重建,4例患者因严重心脏病未建议进行AAA手术。手术患者中13.4%发生了术后心肌缺血并发症,几乎全部发生在有CAD临床证据的患者中。双支或三支血管病变患者的心肌缺血和术前干预比病变较轻的患者更频繁。有症状且患有双支或三支血管CAD的患者在AAA手术后发生心肌缺血的风险很高。初步心肌血运重建可能对这组患者有益。