3α,7α-二羟基-5β-胆烷-24-酸（鹅去氧胆酸）和3α,7β-二羟基-5β-胆烷-24-酸（熊去氧胆酸）的新型衍生物。
Novel derivatives of 3 alpha,7 alpha-dihydroxy-5 beta-cholan-24-oic acid (chenodeoxycholic acid) and 3 alpha,7 beta-dihydroxy-5 beta-cholan-24-oic acid (ursodeoxycholic acid).
作者信息
Kritchevsky D, Poli G, Scolastico C, Sirtori C R
出版信息
Steroids. 1986 Jan;47(1):41-8. doi: 10.1016/0039-128x(86)90075-9.
PMID:3810698
Abstract
Several 7-acyl cheno- and ursodeoxycholic acids were obtained in good yields starting from the corresponding cheno- and ursodeoxycholic acids, by a diacylation-selective hydrolysis procedure. A superior method for the synthesis of the 7-oleyl derivatives, by a selective acylation procedure, is also presented.
摘要
通过二酰化-选择性水解程序，从相应的鹅去氧胆酸和熊去氧胆酸出发，以良好的产率获得了几种7-酰基鹅去氧胆酸和熊去氧胆酸。还介绍了一种通过选择性酰化程序合成7-油酰基衍生物的更优方法。
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