Department of Pediatrics and Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA.
Methods Mol Biol. 2024;2750:107-112. doi: 10.1007/978-1-0716-3605-3_10.
This protocol allows for the detection of a c-Myc tag on alpha-1 antitrypsin (AAT) delivered to species that already have endogenous AAT such as non-human primates allowing reliable and repeatable semi-quantitation of serum levels of AAT.
本方案可检测已表达内源性 AAT（如非人类灵长类动物）的物种中递送到的α-1 抗胰蛋白酶（AAT）上的 c-Myc 标签，从而可靠且可重复地对 AAT 的血清水平进行半定量分析。
