Yao S, Xiong B, Tuo J Y, Qin Y, Meng F D, Xia Y F, Zhang M, Wei S Z
Hubei Cancer Registration Center, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430079, China.
Wufeng Tujia Autonomous County Center for Disease Control and Prevention, Yichang 443413, China.
Zhonghua Zhong Liu Za Zhi. 2023 Dec 23;45(12):1051-1056. doi: 10.3760/cma.j.cn112152-20230403-00145.
To analyze the survival of newly diagnosed malignant tumors in cancer registration areas of Hubei Province from 2013 to 2015. From January 1, 2013 to December 31, 2015, all newly diagnosed malignant tumors were collected from cancer registration areas in Hubei Province, and patients were followed up using a combination of active and passive methods. Cancer survival was analyzed using the strs package in Stata software. Observed and expected survival were calculated using the life table and Ederer Ⅱ methods, and the difference in survival rate of patients with different sex, age, urban and rural areas and different cancer species was compared. From 2013 to 2015, 83 987 new malignant tumors were diagnosed in cancer registration areas in Hubei Province, including 45 742 males (54.46%) and 38245 females (45.54%). The overall 5-year relative survival rate was 41.46%, 34.43% for men and 49.63% for women. With the increase of age, the observed survival rate and relative survival rate of patients of different genders showed a decreasing trend. The 5-year relative survival rate of patients with malignant tumors was 47.58% in urban areas and 26.58% in rural areas. The observed survival rate and relative survival rate in rural areas were significantly lower than those in urban areas. The overall 5-year relative survival rates for common malignancies were 20.61% for lung cancer, 15.36% for liver cancer, 22.89% for esophageal cancer, 34.92% for gastric cancer, and 54.87% for colorectal cancer. In addition, the 5-year relative survival rates of common malignant tumors in women were 78.65% for breast cancer and 52.55% for cervical cancer. In Hubei Province, the survival rate of malignant tumors is different among different genders, regions, age groups and cancer species. Prevention and treatment and health education should be strengthened for malignant tumor patients in rural areas and those with high incidence and low survival rate such as liver cancer and lung cancer, and relevant strategies should be formulated according to the gender and age distribution characteristics of different cancer species.
分析2013年至2015年湖北省癌症登记地区新诊断恶性肿瘤的生存情况。2013年1月1日至2015年12月31日,收集湖北省癌症登记地区所有新诊断的恶性肿瘤患者,并采用主动与被动相结合的方法对患者进行随访。使用Stata软件中的strs包分析癌症生存率。采用寿命表法和EdererⅡ法计算观察生存率和预期生存率,并比较不同性别、年龄、城乡地区及不同癌症种类患者的生存率差异。2013年至2015年,湖北省癌症登记地区共诊断出83987例新的恶性肿瘤患者,其中男性45742例(54.46%),女性38245例(45.54%)。总体5年相对生存率为41.46%,男性为34.43%,女性为49.63%。随着年龄的增加,不同性别的患者观察生存率和相对生存率均呈下降趋势。恶性肿瘤患者的5年相对生存率城市地区为47.58%,农村地区为26.58%。农村地区的观察生存率和相对生存率显著低于城市地区。常见恶性肿瘤的总体5年相对生存率分别为:肺癌20.61%、肝癌15.36%、食管癌22.89%、胃癌34.92%、结直肠癌54.87%。此外,女性常见恶性肿瘤的5年相对生存率分别为:乳腺癌78.65%、宫颈癌52.55%。在湖北省,不同性别、地区、年龄组和癌症种类的恶性肿瘤生存率存在差异。应加强对农村地区以及肝癌、肺癌等高发病率、低生存率的恶性肿瘤患者的防治和健康教育,并根据不同癌症种类的性别和年龄分布特点制定相关策略。