Li H Z, Zhu H T, Chen Y Y, Zheng R S, Jin G F, Du L B, Cheng X D
Department of Cancer Prevention, Zhejiang Cancer Hospital (Zhejiang Cancer Center) /Zhejiang Provincial Office for Cancer Prevention and Control, Hangzhou 310022, China.
Department of Chronic non-communicable Disease Control and Prevention, Yongkang Center for Disease Control and Prevention, Yongkang 321300, China.
Zhonghua Zhong Liu Za Zhi. 2024 Sep 23;46(9):862-870. doi: 10.3760/cma.j.cn112152-20231024-00233.
To analyze epidemiology of gastric cancer five-year survival distribution in Zhejiang population-based cancer registration. The follow-up data of registrated gastric cancer cases diagnosed from 2008 to 2019 in 22 national cancer registry areas of Zhejiang Province were collected and divided into three diagnostic periods: 2008-2011, 2012-2015 and 2016-2019 to calculate five-year observed survival rates (OSRs), five-year relative survival rates (RSRs) and five-year age-standardized relative survival rates (ARSRs). The distribution of population characteristics (including gender, urban/rural, age group and occupation) and clinical characteristics (including the highest diagnostic institution, sub-site, pathological type and degree of differentiation) of gastric cancer survival rates in each period were analysed. 51 663 new cases of gastric cancer in 2008-2019 in the cancer registration area of Zhejiang Province were included in the analysis, and the ARSR of gastric cancer in 2008-2011, 2012-2015 and 2016-2019 showed an increasing trend (39.2%, 41.3% and 44.7%, respectively). In 2016-2019, the ARSR was similar across gender and urban and rural areas (44.4% for men and 45.7% for women; 44.9% in urban areas and 44.2% in rural areas); Among people with different occupations, the ARSR was highest among business and service workers (55.3%), the agriculture, forestry, animal husbandry and fisheries, water conservancy production workers and domestic workers were lower (41.5% and 43.2%, respectively). The highest diagnostic institution was the provincial hospital with a higher gastric cancer survival rate (47.0%) than the municipal (43.4%) and district (43.6%) levels. The ARSR for gastric cancer was relatively high in the lesser curvature (59.7%), pylorus (50.4%), antrum (49.3%), and greater curvature (48.7%), and lowest in cardia (38.9%). Among the major pathological types, adenocarcinoma (NOS) had an ARSR of 48.1%, mucinous adenocarcinoma 41.3%, imprinted cell carcinoma 39.4%, and squamous carcinoma 33.4%. The ARSR for highly differentiated, moderately differentiated, poorly differentiated and undifferentiated gastric cancers were 80.6%, 57.9%, 43.2% and 36.8%, respectively. The 5-year survival rate of gastric cancer in Zhejiang Province is high and on the rise, with similar survival rates in different genders, urban and rural areas, and significant differences in the survival rates of gastric cancer patients with different occupational groups, highest diagnostic institutions, tumour sub-sites, pathological types and differentiation degrees.
分析浙江省基于人群癌症登记的胃癌五年生存分布情况。收集了浙江省22个国家癌症登记地区2008年至2019年诊断的登记胃癌病例的随访数据，并分为三个诊断时期：2008 - 2011年、2012 - 2015年和2016 - 2019年，以计算五年观察生存率（OSR）、五年相对生存率（RSR）和五年年龄标准化相对生存率（ARSR）。分析了各时期胃癌生存率的人群特征（包括性别、城乡、年龄组和职业）和临床特征（包括最高诊断机构、肿瘤亚部位、病理类型和分化程度）分布。浙江省癌症登记地区2008 - 2019年的51663例胃癌新发病例纳入分析，2008 - 2011年、2012 - 2015年和2016 - 2019年胃癌的ARSR呈上升趋势（分别为39.2%、41.3%和44.7%）。2016 - 2019年，不同性别和城乡地区的ARSR相似（男性为44.4%，女性为45.7%；城市地区为44.9%，农村地区为44.2%）；在不同职业人群中，商业和服务业人员的ARSR最高（55.3%），农业、林业、畜牧业、渔业、水利生产工人和家政工人较低（分别为41.5%和43.2%）。最高诊断机构为省级医院，胃癌生存率较高（47.0%），高于市级（43.4%）和区级（43.6%）。胃癌的ARSR在胃小弯（59.7%）、幽门（50.4%）、胃窦（49.3%）和胃大弯（48.7%）相对较高，在贲门（38.9%）最低。在主要病理类型中，腺癌（NOS）的ARSR为48.1%，黏液腺癌为41.3%，印戒细胞癌为39.4%，鳞状细胞癌为33.4%。高分化、中分化、低分化和未分化胃癌的ARSR分别为80.6%、57.9%、43.2%和36.8%。浙江省胃癌的五年生存率较高且呈上升趋势，不同性别、城乡地区的生存率相似，不同职业群体、最高诊断机构、肿瘤亚部位、病理类型和分化程度的胃癌患者生存率存在显著差异。
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