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应用交联透明质酸钠进行臀部容量填充和改善脂肪团凹陷的安全性和有效性研究。

Safety and Efficacy Study of the Application of Redensified Cross-Linked Hyaluronic Acid for Filling Gluteal Volume and Cellulite Depressions.

机构信息

Plastic Surgery & Laser Department, Clínica Robles, 2530 Virrey del Pino St, C1426EGT, Autonomous City of Buenos Aires, Buenos Aires, Argentina.

出版信息

Aesthetic Plast Surg. 2024 Mar;48(6):1181-1192. doi: 10.1007/s00266-023-03739-8. Epub 2023 Dec 18.

DOI:10.1007/s00266-023-03739-8
PMID:38110737
Abstract

PURPOSE

To test the efficacy and safety of cross-linked hyaluronic acid application for filling buttocks and cellulite depressions and its permanence over time.

METHODS

For a period of a year, 25 patients were applied redensified cross-linked hyaluronic acid in the gluteal area. These patients were all 23-45-year-old women with little fat to be removed. The product used is composed of hyaluronic acid with high cross-linking and redensification which allows it to maintain shape and durability over time. All patients underwent tumescent anesthesia with neuroleptic sedation in the operating room. The procedure was regarded as minimal (container, sterile gloves, and surgical field). The amount applied for gluteal augmentation varied from 50 to 100 ml per application area and according to the patient's needs. For the filling of cellulite depressions, the application was up to 3 cc per depression and up to a total of 40 ml. The maximum volume used per patient in the buttocks did not exceed 200 ml, and it did not exceed 40 ml in cellulite depressions.

RESULTS

A group of patients was treated in the upper and middle third of the buttocks in superficial and deep subcutaneous layers and in cellulite depressions. Very good results have been obtained without any major complications.

CONCLUSIONS

The use of redensified cross-linked hyaluronic acid of non-animal origin is therefore an option for gluteal augmentation and cellulite depressions. Although the product degrades over time, after 12 months, 44% of treated patients rated their results as highly or very much improved, 36% as improved, 16% rated the improvement as poor, and one patient (4%) was dissatisfied.

LEVEL OF EVIDENCE IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

目的

测试交联透明质酸用于填充臀部和蜂窝组织凹陷的疗效和安全性及其随时间的持久性。

方法

在一年的时间里,25 名患者在臀部区域应用了再水合交联透明质酸。这些患者均为 23-45 岁、无需去除多余脂肪的女性。所用产品由具有高交联和再水合特性的透明质酸组成,这使其能够随时间保持形状和耐久性。所有患者均在手术室接受肿胀麻醉和神经安定镇静。该程序被视为微创(容器、无菌手套和手术区域)。每次应用于臀部增大的用量为 50-100ml/应用区域,并根据患者的需求而定。对于填充蜂窝组织凹陷,每次应用可达 3cc/每个凹陷,总量可达 40ml。每位患者在臀部使用的最大体积不超过 200ml,在蜂窝组织凹陷处不超过 40ml。

结果

一组患者在上臀部的中三分之一、浅和深皮下层以及蜂窝组织凹陷处进行了治疗。结果非常好,没有出现任何重大并发症。

结论

因此,使用非动物源性再水合交联透明质酸是臀部增大和蜂窝组织凹陷的一种选择。尽管该产品随时间降解,但在 12 个月后,44%接受治疗的患者认为其效果高度或非常改善,36%认为改善,16%认为改善差,1 名患者(4%)不满意。

证据等级 IV:本杂志要求作者为每篇文章分配一个证据等级。有关这些循证医学等级的完整描述,请参阅目录或在线作者指南 www.springer.com/00266 。

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