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酒精使用障碍与阻塞性睡眠呼吸暂停风险之间的关联。

Association between alcohol use disorder and risk of obstructive sleep apnea.

作者信息

Ko Jisu, Lim Jae Hyeok, Kim Dan Bi, Joo Min Jeong, Jang Yun Seo, Park Eun-Cheol, Shin Jaeyong

机构信息

Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.

Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.

出版信息

J Sleep Res. 2024 Aug;33(4):e14128. doi: 10.1111/jsr.14128. Epub 2023 Dec 19.

DOI:10.1111/jsr.14128
PMID:38112217
Abstract

Obstructive sleep apnea (OSA) is a common sleep disorder characterised by recurrent upper airway collapse during sleep. Alcohol consumption has been linked to an increased risk of OSA due to its effects on the upper airway and body mass index (BMI). We aimed to investigate the correlation between alcohol use disorders and OSA. We used 11,859 participants data from Korean National Health and Nutrition Examination Surveys. The variable of interest was alcohol use disorder, measured using the Alcohol Use Disorders Identification Test, and the dependent variable was the risk of OSA, measured using the Snoring, Tiredness, Observed apnea, high blood Pressure, BMI, age, neck circumference, and male gender questionnaires. Multiple logistic regression was used to assess the association between alcohol use disorder and OSA risk after adjusted analysis. A significant association was found between alcohol use disorder and OSA (adjusted odds ratio [aOR] 2.14, 95% confidence interval [CI] 1.93-2.37). In the unemployed group, those with alcohol use disorder had the highest odds of being at risk of OSA compared with those who did not have this disorder (aOR 2.45, 95% CI 2.04-2.95). The OSA risk increased as the snoring frequency, amount of alcohol consumed, and frequency of binge drinking increased. This study suggests an association between alcohol use disorders and the risk of OSA. The frequency of alcohol consumption, quantity of alcohol consumed, and snoring frequency were associated with the risk of OSA. Therefore, ceasing alcohol consumption is recommended as an effective approach to enhancing sleep quality.

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见的睡眠障碍,其特征是睡眠期间上呼吸道反复塌陷。饮酒因其对上呼吸道和体重指数(BMI)的影响,与患OSA的风险增加有关。我们旨在研究酒精使用障碍与OSA之间的相关性。我们使用了韩国国家健康与营养检查调查中11859名参与者的数据。感兴趣的变量是酒精使用障碍,通过酒精使用障碍识别测试来衡量,因变量是OSA的风险,通过打鼾、疲劳、观察到的呼吸暂停、高血压、BMI、年龄、颈围和男性性别问卷来衡量。在进行调整分析后,使用多因素逻辑回归来评估酒精使用障碍与OSA风险之间的关联。发现酒精使用障碍与OSA之间存在显著关联(调整后的优势比[aOR]为2.14,95%置信区间[CI]为1.93 - 2.37)。在失业组中,与没有这种障碍的人相比,患有酒精使用障碍的人患OSA风险的几率最高(aOR为2.45,95%CI为2.04 - 2.95)。随着打鼾频率、饮酒量和暴饮频率的增加,OSA风险也增加。这项研究表明酒精使用障碍与OSA风险之间存在关联。饮酒频率、饮酒量和打鼾频率与OSA风险相关。因此,建议戒酒作为提高睡眠质量的有效方法。

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