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印度奥里萨邦一个农村社区中阻塞性睡眠呼吸暂停高危人群的患病率和危险因素:一项基于社区的横断面研究。

Prevalence and risk factors of people at-risk of obstructive sleep apnea in a rural community of Odisha, India: a community based cross-sectional study.

机构信息

S.C.B. Medical College, Cuttack, Odisha, India.

Department of Community Medicine, S.C.B. Medical College, Cuttack, Odisha, India.

出版信息

Sleep Med. 2019 Jun;58:42-47. doi: 10.1016/j.sleep.2019.03.014. Epub 2019 Mar 28.

Abstract

BACKGROUND

Obstructive sleep apnea (OSA) is a progressive sleep disordered breathing condition characterized by repeated episodes of upper airway collapse during sleep. Despite being the most common sleep apnea, it often remains undiagnosed and untreated, especially in rural communities. There is a paucity of literature estimating the prevalence of the disease and associated risk factors from the rural population of Odisha.

METHODS

It is a cross-sectional study that was conducted in a rural community of Odisha, India to find out the prevalence of people living with the risk of OSA. Multi-staged sampling was done. Participants were evaluated using the Berlin questionnaire (BQ) after obtaining informed consent. Data were analyzed using SPSS with the significance level set at 95%. Univariate and multivariate analysis was done to evaluate the risk factors associated with the condition.

RESULTS

Out of 200 community dwellers surveyed using the BQ, 25% had a high likelihood of OSA. Among these high risk subjects, snoring was reported by 70%, excessive daytime sleepiness by 50%. Out of those who were at risk of OSA, 28% were smokers and 48% reported alcohol use. The associated risk factors were age >35 years (OR = 4.5, 95% CI = 1.4-13.8, p < 0.05), BMI ≥ 25 kg/m (aOR = 3.5, 95% CI = 1.2- 10.5, p < 0.05), alcoholism (aOR = 4.5, 95% CI = 1.8-11.1, p = 0.001), and hypertension (aOR = 11.5, 95% CI = 4.7-28, p < 0.001). The prevalence was not affected by the type of diet (vegetarian vs non-vegetarian), use of tobacco or tea consumption.

CONCLUSION

OSA is highly prevalent in the rural community of Odisha. Independent risk factors associated with such subjects were obesity, regular alcohol consumption, and hypertension. Further prevalence studies are recommended.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)是一种进行性睡眠呼吸紊乱疾病,其特征是睡眠期间上呼吸道反复塌陷。尽管这是最常见的睡眠呼吸暂停,但它在农村社区往往未被诊断和治疗,尤其是在农村社区。来自奥里萨邦农村地区的关于该疾病的患病率和相关危险因素的文献很少。

方法

这是一项在印度奥里萨邦农村社区进行的横断面研究,旨在发现患有 OSA 风险的人群的患病率。采用多阶段抽样。在获得知情同意后,使用柏林问卷(BQ)对参与者进行评估。使用 SPSS 进行数据分析,置信水平设定为 95%。进行单变量和多变量分析以评估与该疾病相关的危险因素。

结果

在使用 BQ 调查的 200 名社区居民中,有 25%的人有患 OSA 的高可能性。在这些高风险人群中,70%的人打鼾,50%的人白天过度嗜睡。在有 OSA 风险的人群中,28%的人吸烟,48%的人饮酒。相关的危险因素是年龄>35 岁(OR=4.5,95%CI=1.4-13.8,p<0.05)、BMI≥25kg/m(aOR=3.5,95%CI=1.2-10.5,p<0.05)、酗酒(aOR=4.5,95%CI=1.8-11.1,p=0.001)和高血压(aOR=11.5,95%CI=4.7-28,p<0.001)。饮食类型(素食与非素食)、烟草使用或茶消费对患病率没有影响。

结论

OSA 在奥里萨邦农村社区的患病率很高。与这些人群相关的独立危险因素是肥胖、规律饮酒和高血压。建议进行进一步的患病率研究。

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