Kucera H, Genger H, Wagner G
Wien Klin Wochenschr. 1986 Dec 5;98(23):785-8.
The separation of FIGO stage I b cervical carcinoma into a new histological stage I b1 and a stage I c (deep infiltration confined to the cervix) leads to an essential difference in therapeutic results. 5-year survival of 152 cases consigned to the new stage I b1 was 92%, whereas that of 95 cases of the new stage I c was only 77%. Hence, 5-year survival of stage I c patients is lower than of FIGO stage II a (83%). Contrary to our earlier practice, since 1976 all stage I c cases have received postoperative irradiation (Cobalt60). 5-year survival of 75 stage I c cases without lymph node metastasis was 83% when treated by surgery alone; 5-year survival of 22 similar cases treated by surgery and postoperative irradiation was 82%. There is no benefit of postoperative irradiation in cases of stage I c cervical carcinoma when the lymph nodes are not affected.
国际妇产科联盟(FIGO)将I b期宫颈癌重新划分为新的组织学I b1期和I c期(仅局限于宫颈的深部浸润),这导致了治疗结果的本质差异。归入新I b1期的152例患者的5年生存率为92%,而新I c期的95例患者的5年生存率仅为77%。因此,I c期患者的5年生存率低于FIGO II a期(83%)。与我们之前的做法相反,自1976年以来,所有I c期病例均接受了术后放疗(钴60)。75例无淋巴结转移的I c期病例单纯手术治疗的5年生存率为83%;22例类似病例接受手术及术后放疗的5年生存率为82%。对于未发生淋巴结转移的I c期宫颈癌病例,术后放疗并无益处。