Moniez V, Bauer V, Plocoste V, Magnin G, Avril A
Service de Gynécologie-Obstétrique, Centre Hospitalier Régional, Hôpital Jean-Bernard, Poitiers.
Rev Fr Gynecol Obstet. 1990 May;85(5):321-7.
The results of a retrospective study of 74 women under the age of 35, treated invasive cervical cancer, stage I and stage II, between 1973 and 1985, were compared with those obtained in 547 women over 35, treated during the same period of time for a similar cervical cancer. The treatment consisted of: association radium therapy-surgery for stages IB less than 25 mm and II A moderately extended and an association radiotherapy-radium therapy for stages IB greater than 25 mm and II A extended, II B and II C. A better distribution per stage is found in women under 35, identical regarding the histological type with 5-year survival identical in both groups at the same stage. Relapses or recurrences occur much earlier in younger women. In the literature, the age as a prognosis factor is very much controverted. On the contrary, other factors should be taken into consideration: clinical stage, node invasion, size and volume of the tumor, depth of infiltration of the cervix.
对1973年至1985年间接受治疗的74名35岁以下的I期和II期浸润性宫颈癌女性患者的回顾性研究结果，与同期接受类似宫颈癌治疗的547名35岁以上女性患者的结果进行了比较。治疗方法包括：对于IB期小于25mm和II A期中度扩展的患者，采用镭疗-手术联合治疗；对于IB期大于25mm和II A期扩展、II B期和II C期的患者，采用放疗-镭疗联合治疗。35岁以下女性患者各阶段的分布情况更好，两组在组织学类型方面相同，同阶段的5年生存率也相同。年轻女性的复发或再发情况出现得更早。在文献中，年龄作为预后因素存在很大争议。相反，应考虑其他因素：临床分期、淋巴结侵犯、肿瘤的大小和体积、宫颈的浸润深度。
