Hansen J B, Nielsen P E, Leick V, Buchardt O
Hoppe Seylers Z Physiol Chem. 1979 Jun;360(6):721-4. doi: 10.1515/bchm2.1979.360.1.721.
The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.
描述了比活度为1.25 Ci/mmol的[3H]氯霉素及其赤型非对映异构体的合成，以及[3H]氯霉素进一步转化为一系列叠氮基和重氮基取代衍生物的过程。这些化合物的抗生素活性被认为不足以用作光亲和标记物。
