[Is the determination of glycosylated hemoglobins in neonatal macrosomia useful?].

170 blood samples of mother and child of patients with and without risk of diabetes as well as of mothers with macrosomic newborns have been examined immediately after delivery. The procentual rate of glycosylated hemoglobin (GHb) was determined by an affinity chromatographic method. The mean of the GHb values of the children was 37% lower compared to the values of their mothers and in this showed a linear correlation. A dependence on the deviation of weight of the mothers from the Broca normal weight was found but not a dependence on the gain of weight during pregnancy, on height and age. In the GHb values of mothers and children a significant dependence on the weight of the mother before pregnancy was seen. There was no relation of the glycosylated hemoglobins to the birth weight of the newborn in regard to the age of pregnancy and the sex of the children. To our opinion the GHb measurement can therefore not be used for the diagnosis of latent diabetes in pregnancy in the case of newborn macrosomia.