Kenny J, Cohn L, Shemin R, Collins J J, Plappert M, Sutton M G
Am J Cardiol. 1987 Feb 1;59(4):341-5. doi: 10.1016/0002-9149(87)90810-1.
Doppler echocardiographic studies were performed in 21 consecutive patients (mean age 56 +/- 11 years) to evaluate postoperative results of mitral ring anuloplasty. All patients were symptomatic and all had clinically severe isolated mitral regurgitation (MR). The origin of MR was myxomatous degeneration, coronary artery disease, rheumatic heart disease or congestive cardiomyopathy. In 20 patients ring anuloplasty was performed using the Carpentier ring and 1 patient using the Duran ring. Postoperative Doppler echocardiographic studies were performed to detect and semiquantitate residual MR by flow mapping and to identify left ventricular inflow or outflow obstruction. The severity of MR was assessed by flow mapping in the left atrium and graded from I to IV in increasing severity. Blood flow velocity spectra were recorded from the left ventricular outflow tract during systole and from the left ventricle subjacent to the mitral valve during diastole. Pressure half-time, mitral valve area and mitral valve gradient were derived from digitized mitral diastolic flow velocity spectra. After ring valvuloplasty, 9 patients had no MR and 6 had grade I, 3 grade II, 2 grade III and 1 patient grade IV MR. Peak diastolic mitral valve gradient was 8 +/- 4 mm Hg, mean diastolic gradient was 3 +/- 2 mm Hg and pressure half-time was 83 +/- 17 ms, representing a calculated mean mitral valve area of 2.9 +/- 0.8 cm. Peak velocity in the left ventricular outflow tract was 0.9 +/- 0.2 m/s, indicating no obstruction to outflow. Our study confirms that mitral ring valvuloplasty produces a significant reduction in severity of MR, and this is achieved without obstructing left ventricular inflow or outflow.
对21例连续患者(平均年龄56±11岁)进行了多普勒超声心动图研究,以评估二尖瓣环成形术的术后结果。所有患者均有症状,且均患有临床上严重的单纯二尖瓣反流(MR)。MR的病因是黏液瘤样变性、冠状动脉疾病、风湿性心脏病或充血性心肌病。20例患者使用Carpentier环进行环成形术,1例患者使用Duran环。术后进行多普勒超声心动图研究,通过血流图检测和半定量残余MR,并识别左心室流入或流出道梗阻。通过左心房血流图评估MR的严重程度,严重程度从I级到IV级递增。在收缩期从左心室流出道记录血流速度频谱,在舒张期从二尖瓣下方的左心室记录血流速度频谱。压力减半时间、二尖瓣面积和二尖瓣梯度由数字化的二尖瓣舒张期血流速度频谱得出。环瓣膜成形术后,9例患者无MR,6例为I级,3例为II级,2例为III级,1例为IV级MR。二尖瓣舒张期峰值梯度为8±4mmHg,平均舒张期梯度为3±2mmHg,压力减半时间为83±17ms,计算得出的平均二尖瓣面积为2.9±0.8cm²。左心室流出道峰值速度为0.9±0.2m/s,表明无流出道梗阻。我们的研究证实,二尖瓣环瓣膜成形术可显著降低MR的严重程度,且在不阻碍左心室流入或流出的情况下实现这一目标。