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结肠镜治疗结肠急性假性梗阻

Colonoscopic therapy of acute pseudoobstruction of the colon.

作者信息

Nano D, Prindiville T, Pauly M, Chow H, Ross K, Trudeau W

出版信息

Am J Gastroenterol. 1987 Feb;82(2):145-8.

PMID:3812419
Abstract

All patients with the diagnosis of acute colonic pseudoobstruction at the University of California, Davis Medical Center from 1979-1985 were reviewed. These 25 patients were initially treated conservatively (nasogastric tube/rectal tube/enemas) and this was successful in eight of 25 patients (32%). The remaining 17 patients (68%) unresponsive to conservative therapy received endoscopic intervention, either colonoscopic suction decompression (CSD) or colonic suction decompression with proximal colonic tube placement (CDT) for continuous decompression. Of the endoscopic procedures performed, 13/17 (76%) resulted in successful acute decompression. Recurrences occurred in 6/13 (45%) (3/7 in the colonoscopic suction decompression group and three of six in the colonic tube placement group). In the 10 failures, six further procedures were attempted, but only one was successful. These patients were then treated conservatively. There were no instances of colonic perforation. Acute pseudoobstruction in our experience is a benign entity that can be safely and successfully treated nonsurgically. Colonoscopic suction decompression is often initially successful but has a high frequency of recurrence. Newer techniques to prevent recurrence, i.e., colonic tube placement, are of potential benefit but presently have technical problems.

摘要

对1979年至1985年期间在加利福尼亚大学戴维斯分校医疗中心诊断为急性结肠假性梗阻的所有患者进行了回顾性研究。这25例患者最初接受了保守治疗(鼻胃管/直肠管/灌肠),25例患者中有8例(32%)治疗成功。其余17例(68%)对保守治疗无反应的患者接受了内镜干预,即结肠镜抽吸减压(CSD)或近端结肠置管的结肠抽吸减压(CDT)以持续减压。在内镜操作中,13/17例(76%)成功实现急性减压。复发发生在6/13例(45%)(结肠镜抽吸减压组7例中有3例,结肠置管组6例中有3例)。在10例失败病例中,又尝试了6次操作,但仅1例成功。这些患者随后接受了保守治疗。没有结肠穿孔的病例。根据我们的经验,急性假性梗阻是一种良性疾病,可以通过非手术方式安全、成功地治疗。结肠镜抽吸减压通常最初是成功的,但复发频率较高。预防复发的新技术,即结肠置管,具有潜在益处,但目前存在技术问题。

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