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Impella驱动的高危经皮冠状动脉介入治疗:一个新颖的、单非手术中心病例报告。

Impella-Driven High-Risk Percutaneous Coronary Intervention: A Novel, Single Non-Surgical-Centre Case Report.

作者信息

Ajagbe Temitope, Bello Olamide, Fagbemi Ona, Ungvari Tamas

机构信息

Cardiology, Royal Cornwall Hospital Treliske, Truro, GBR.

Haematology, Somerset NHS Foundation Trust, Taunton, GBR.

出版信息

Cureus. 2023 Nov 20;15(11):e49128. doi: 10.7759/cureus.49128. eCollection 2023 Nov.

Abstract

Complex percutaneous coronary intervention (PCI) procedures have been routinely performed in non-surgical centres in the UK for more than two decades. These procedures follow strict guidelines and recommendations by the British Cardiovascular Intervention Society to ensure a more effective running of PCI programs. Even more so, expected guiding principles necessary for the safe optimisation of complex PCI procedures have also been created.  An 81-year-old male was admitted with non-ST-elevation myocardial infarction (NSTEMI) and severely impaired left ventricle ejection fraction (LVEF; 26% according to the cardiac MRI report). Angiogram findings revealed severe multiple-vessel coronary artery disease affecting the following arteries: right coronary artery (RCA), left anterior descending artery (LAD), left circumflex artery (LCx), and intermediate artery (IM). There was also severe disease in the distal left main stem (LMS) bifurcation extending to the ostia of the LAD, LCx, and IM branches. Following a multidisciplinary meeting, the patient underwent Impella-supported high-risk PCI (complex PCI) using the DK crush technique with no peri- and post-procedure complication and a significant LV function improvement (45-49%). This is the first known case of this procedure performed at the Royal Cornwall Hospital in Treliske (RCHT), Truro, Cornwall. This case report highlights that when the decision to choose between coronary artery bypass graft (CABG) and PCI is not straightforward following an individualised risk-stratification scoring system analysis and in the setting of patient comorbidities, a high-risk PCI supported with the Impella device is a suitable alternative with promising short-term and long-term outcomes.

摘要

在英国,复杂经皮冠状动脉介入治疗(PCI)手术已在非手术中心常规开展了二十多年。这些手术遵循英国心血管介入学会的严格指南和建议,以确保PCI项目更有效地运行。更重要的是,还制定了复杂PCI手术安全优化所需的预期指导原则。一名81岁男性因非ST段抬高型心肌梗死(NSTEMI)入院,左心室射血分数严重受损(根据心脏磁共振成像报告为26%)。血管造影结果显示严重的多支冠状动脉疾病,累及以下动脉:右冠状动脉(RCA)、左前降支动脉(LAD)、左旋支动脉(LCx)和中间动脉(IM)。左主干(LMS)远端分叉处也有严重病变,延伸至LAD、LCx和IM分支的开口处。经过多学科会诊,患者接受了使用DK挤压技术的Impella支持的高风险PCI(复杂PCI),术中及术后均无并发症,左心室功能显著改善(45%-49%)。这是在康沃尔郡特鲁罗的特雷利斯基皇家康沃尔医院(RCHT)进行的首例已知该手术病例。本病例报告强调,在个体化风险分层评分系统分析后,当在冠状动脉旁路移植术(CABG)和PCI之间做出选择不明确且存在患者合并症的情况下,Impella设备支持的高风险PCI是一种合适的替代方案,具有良好的短期和长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7c5/10732543/77419aa46c3b/cureus-0015-00000049128-i01.jpg

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