Sijmons W J L, Krijt L L, Bruggink R, Ongkosuwito E M, Kuijpers M A R
Department of Dentistry, Section of Orthodontics and Craniofacial Biology, Radboud University Nijmegen Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands.
3DLAB The Netherlands, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands.
Cleft Palate Craniofac J. 2025 Apr;62(4):676-682. doi: 10.1177/10556656231221658. Epub 2023 Dec 21.
ObjectiveTo determine possible effects of unilateral alveolar cleft closure on internal nasal volume and external nasolabial surface.DesignRetrospective, single-arm, cohort study.SettingInstitutional, tertiary care.PatientsPatients with complete unilateral cleft lip, alveolus, and palate (CUCLAP), who underwent closure of the alveolar cleft with autologous bone graft (ABG) at the age of 9-11 years, with cone beam computed tomography (CBCT) and/or three-dimensional (3D) stereophotogrammetry images taken before and one year after the ABG procedure.InterventionsABG-pocedure in patients with CUCLAP.Main Outcome MeasuresThe influence of ABG on the internal and external nasal morphology.ResultsA total of 28 patients (21M/7F, 14R/14L) were divided into internal (CBCT) and external (3D-stereophotogrammetry) measurement subgroups. The external nasolabial surface showed a significant decrease of the angle alar curvature right-subnasale-alar curvature left (-1.99°; = .02; 95% CI -2.61, -0.36) and an increase of the linear measurement between these points (+1.01 mm; = .03; 95% CI: 0.11, 1.91). No significant differences were found when comparing the distance maps of the affected side with the non-affected side (= .50, 95% CI: -0.20, 0.29).ConclusionsClosure of the alveolar cleft in CUCLAP patients with ABG did not affect the internal nasal volume, but significantly affected the external nasal surface. The procedure resulted in the nose becoming wider because both alar curvatures moved caudally and laterally relative to the subnasale.
目的
确定单侧牙槽嵴裂修复对鼻腔内部容积和鼻唇外部表面的可能影响。
设计
回顾性、单臂队列研究。
设置
机构性三级医疗中心。
患者
9至11岁接受自体骨移植(ABG)修复牙槽嵴裂的完全性单侧唇腭裂(CUCLAP)患者,在ABG手术前和术后一年拍摄锥形束计算机断层扫描(CBCT)和/或三维(3D)立体摄影测量图像。
干预措施
对CUCLAP患者进行ABG手术。
主要观察指标
ABG对鼻腔内外形态的影响。
结果
共28例患者(21例男性/7例女性,14例右侧/14例左侧)分为内部(CBCT)和外部(3D立体摄影测量)测量亚组。鼻唇外部表面显示右侧鼻翼曲率-鼻下点-左侧鼻翼曲率角度显著减小(-1.99°;P = 0.02;95%可信区间-2.61,-0.36),这些点之间的线性测量增加(+1.01 mm;P = 0.03;95%可信区间:0.11,1.91)。比较患侧与未患侧的距离图时未发现显著差异(P = 0.50,95%可信区间:-0.20,0.29)。
结论
CUCLAP患者采用ABG修复牙槽嵴裂不影响鼻腔内部容积,但显著影响鼻外部表面。该手术导致鼻子变宽,因为两侧鼻翼曲率相对于鼻下点均向尾侧和外侧移动。