Gollmann-Tepeköylü Can, Holfeld Johannes, Naegele Felix, Grimm Michael, Bonaros Nikolaos
Department of Cardiac Surgery, Medical University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria.
Eur Heart J Case Rep. 2023 Dec 18;7(12):ytad617. doi: 10.1093/ehjcr/ytad617. eCollection 2023 Dec.
Failing bioprosthesis is an emerging issue due to (i) a shift towards liberal bioprosthesis implantation instead of mechanical prosthesis and (ii) an ageing population. Management of high-risk patients with bioprosthesis degeneration remains challenging.
An 82-year-old patient with history of aortic and mitral valve replacement six years before presents with severe dyspnoea. Echocardiograpic assessment reveals (i) structural valve degeneration of the mitral prosthesis (severe stenosis and regurgitation) with concomitant major annular calcifications and (ii) structural valve degeneration of the aortic prosthesis with low-flow, low-gradient restenosis. Due to mitral annular calcifications, the risk of double valve re-replacement and the age of the patient conventional reoperation was deemed very high. The patient is evaluated for transapical double valve implantation. This option is rejected due to the high risk of left ventricular outflow obstruction. The patient is treated with an open transcatheter double valve-in-valve procedure at the following sequence: leaflet resection of the mitral bioprosthesis, mitral valve implantation and fixation under direct view, leaflet resection of the aortic bioprosthesis, and valve frame cracking and aortic valve implantation under direct view. Post-bypass echocardiography shows neither left ventricular outflow tract obstruction nor paravalvular leak or prosthesis dysfunction. The patient is extubated on the first post-operative day and transferred to normal care unit.
Open transcatheter double valve-in-valve replacement for degenerated bioprostheses on the arrested heart might be a valuable alternative to treat selected high-risk patients with bioprosthetic valve degeneration.
由于(i)生物假体植入的倾向从机械假体转向更为宽松的生物假体植入,以及(ii)人口老龄化,生物假体功能衰竭成为一个新出现的问题。对生物假体退化的高危患者进行管理仍然具有挑战性。
一名82岁患者,6年前有主动脉瓣和二尖瓣置换史,现出现严重呼吸困难。超声心动图评估显示:(i)二尖瓣假体结构瓣膜退化(严重狭窄和反流),伴有主要瓣环钙化;(ii)主动脉假体结构瓣膜退化,伴有低流量、低梯度再狭窄。由于二尖瓣环钙化、双瓣再次置换的风险以及患者的年龄,传统再次手术被认为风险非常高。对该患者进行经心尖双瓣植入评估。由于左心室流出道梗阻风险高,该方案被否决。患者接受了开放经导管双瓣瓣中瓣手术,顺序如下:二尖瓣生物假体瓣叶切除、直视下二尖瓣植入和固定、主动脉生物假体瓣叶切除、瓣膜框架破裂及直视下主动脉瓣植入。体外循环后超声心动图显示既无左心室流出道梗阻,也无瓣周漏或假体功能障碍。患者术后第一天拔管,转至普通护理病房。
在心脏停搏时对退化的生物假体进行开放经导管双瓣瓣中瓣置换可能是治疗部分生物假体瓣膜退化高危患者的一种有价值的替代方法。