Hamad Mohammad Adam, Williams Andrew, Kneebusch Jamie, Butala Niyati
Clinical Pharmacist, Western University of Health Sciences College of Pharmacy, Pomona, California; Clinical Pharmacist, Riverside University Health Systems Medical Center, Moreno Valley, California.
Health Sciences Assistant Clinical Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California-San Diego, La Jolla, California.
Ment Health Clin. 2023 Oct 2;13(5):233-238. doi: 10.9740/mhc.2023.10.233. eCollection 2023 Oct.
Urinary tract infections (UTIs) are one of the most common indications for antibiotic use; patients with psychiatric disorders have a greater risk for UTI compared with patients without these disorders. However, there is little guidance on how best to manage antibiotic therapy in psychiatric hospitals. This study assessed the impact of a Board Certified Psychiatric Pharmacist (BCPP)-driven guideline on managing UTI treatment in an acute psychiatric hospital.
The guideline was developed by the psychiatric pharmacy team and distributed to internists, psychiatrists, and pharmacists. Preintervention data were assessed for patients admitted between November 30, 2019, and February 23, 2020; postintervention data were assessed from February 25, 2020, to April 24, 2020. All patients ages 13 years and older who were admitted and had orders for an antibiotic to treat a UTI were included in this study. Appropriate UTI management was defined as an appropriate agent, dose, route, and frequency per the treatment guideline. Additionally, the following criteria were to be ordered and assessed to be deemed appropriate: urinalysis, urine culture, complete blood count, basic or complete metabolic panel, temperature, and subjective symptoms.
Before intervention, 19.0% of antibiotic orders were appropriate; after intervention, 46.7% of antibiotic orders were appropriate ( = .048).
The implementation of a BCPP-driven treatment algorithm was associated with a significant increase in appropriate antibiotic regimens for the treatment of UTIs in patients admitted to a psychiatric hospital.
尿路感染(UTIs)是抗生素使用最常见的指征之一;与没有精神疾病的患者相比,患有精神疾病的患者发生UTI的风险更高。然而,对于精神病医院如何最好地管理抗生素治疗,几乎没有相关指导。本研究评估了由董事会认证的精神科药剂师(BCPP)推动的指南对急性精神病医院UTI治疗管理的影响。
该指南由精神科药房团队制定,并分发给内科医生、精神科医生和药剂师。对2019年11月30日至2020年2月23日入院患者的干预前数据进行评估;对2020年2月25日至2020年4月24日的干预后数据进行评估。本研究纳入了所有13岁及以上入院且有使用抗生素治疗UTI医嘱的患者。适当的UTI管理被定义为根据治疗指南使用适当的药物、剂量、途径和频率。此外,还应开具并评估以下标准以判定为适当:尿液分析、尿培养、全血细胞计数、基本或完整代谢指标、体温和主观症状。
干预前,19.0%的抗生素医嘱是适当的;干预后,46.7%的抗生素医嘱是适当的(P = 0.048)。
在精神病医院住院患者中,实施由BCPP推动的治疗算法与治疗UTI的适当抗生素方案显著增加相关。