Adams C, Baubion N, Le Pailleur C, Gorins D, Tabone X, Weiss L, Heulin A, Vacheron A
Ann Med Interne (Paris). 1986;137(5):391-4.
Five cases of degenerative mitral incompetence due to rupture of the chordae tendinae in patients over 70 years of age were reviewed to determine the clinical features of this pathology which is not rare in elderly patients. Chordal rupture usually involves the posterior leaflet and is a sign of generalised disease of the mitral apparatus of two main types: myxoid infiltration or pellucid degeneration. Although the clinical syndrome of rupture is rare (10 p. 100), the mechanism of the mitral regurgitation can be identified by 2D echocardiography with a sensitivity of 92 p. 100, and the consequences of regurgitation on the left ventricle can also be evaluated. Rapid progression to acute cardiac failure is often observed and early surgical cure may be necessary (valvular replacement with a bioprosthesis is more common than mitral valvuloplasty). Further justification for this surgical approach is the improved myocardial protection which has reduced the perioperative mortality rate to less than 10 p. 100.
回顾了5例70岁以上因腱索断裂导致退行性二尖瓣关闭不全的病例,以确定这种在老年患者中并不罕见的病理情况的临床特征。腱索断裂通常累及后叶,是二尖瓣装置两种主要类型的全身性疾病的征象:黏液样浸润或透明变性。虽然断裂的临床综合征很少见(10/100),但二维超声心动图可识别二尖瓣反流的机制,敏感性为92/100,还可评估反流对左心室的影响。常观察到迅速进展为急性心力衰竭,可能需要早期手术治愈(生物假体瓣膜置换比二尖瓣成形术更常见)。这种手术方法的进一步依据是心肌保护的改善,已将围手术期死亡率降低至10/100以下。