Boughton B J
J Clin Pathol. 1979 Jun;32(6):523-7. doi: 10.1136/jcp.32.6.523.
The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinoma. In normal pregnant women, 6% showed similar increases in anti-i titres.
胎儿抗原i已通过间接免疫荧光法在脐带红细胞和胎盘滋养层细胞上得到证实。一名患有播散性绒毛膜癌的患者产生了高效价的抗-i冷凝集素,在另外六名接受治疗的绒毛膜癌患者中,有四名患者的抗-i效价略有升高。在正常孕妇中,6%的人抗-i效价也有类似升高。