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绒毛膜癌中的抗-i冷凝集素:滋养层i抗原。

Anti-i cold agglutinins in choriocarcinomatosis: trophoblastic i antigen.

作者信息

Boughton B J

出版信息

J Clin Pathol. 1979 Jun;32(6):523-7. doi: 10.1136/jcp.32.6.523.

Abstract

The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinoma. In normal pregnant women, 6% showed similar increases in anti-i titres.

摘要

胎儿抗原i已通过间接免疫荧光法在脐带红细胞和胎盘滋养层细胞上得到证实。一名患有播散性绒毛膜癌的患者产生了高效价的抗-i冷凝集素,在另外六名接受治疗的绒毛膜癌患者中,有四名患者的抗-i效价略有升高。在正常孕妇中,6%的人抗-i效价也有类似升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55d6/1145731/01647b650221/jclinpath00454-0003-a.jpg

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