Department of Health Medicine Center, The Second Hospital Affiliated to Chongqing Medical University, Chongqing, China.
School of Public Health, Chongqing Medical University, Chongqing, China.
Medicine (Baltimore). 2023 Dec 22;102(51):e36798. doi: 10.1097/MD.0000000000036798.
To confirm whether ocular symptoms and complaints related to the COVID-19 infection persist after recovery. A cross-sectional study was conducted on people who came to the healthcare center for regular physical examinations when the lockdown lifted for nearly 1 month. Ophthalmologists performed comprehensive ocular examinations. The infection history of COVID-19 was identified by a self-reported reverse transcription-PCR (RT-PCR) test of a nasopharyngeal swab sample for SARS-CoV-2 or a novel coronavirus antigen test with self-reported typical infection symptoms. Demographic data was collected from their healthcare reports. Ocular history and ocular symptoms were collected through face-to-face interviewing. Of a total of 308 participants, 264 (85.7%) reported COVID-19 infection; 73 (27.65%) of infected persons complained of various ocular symptoms during or after infection; and only 15 (5.68%) persons reported ocular symptoms after recovery. Infection significantly increased the complaints of red eye and eye pain compared to the time before knockdown. There were no significant differences between infections and noninfectious infections in various ocular examinations at the time of examination. The duration between the day of infection onset and examination day was unrelated to all ocular examinations. COVID-19 infection can lead to some ocular symptoms, especially conjunctival congestion and ocular pain in the infective stage, but may not cause persistent ocular symptoms in about 1 month after recovery. The results of this study may help relieve public concerns about coronavirus infection in the eyes. However, more studies on various coronavirus infections, with large sample sizes, are warranted in multi-center and community-based populations.
为了确认与 COVID-19 感染相关的眼部症状和不适是否在康复后持续存在。在封锁解除近 1 个月后，对前来医疗中心进行常规体检的人群进行了一项横断面研究。眼科医生进行了全面的眼部检查。通过对 SARS-CoV-2 的鼻咽拭子样本进行自我报告的逆转录-PCR（RT-PCR）检测或具有自我报告的典型感染症状的新型冠状病毒抗原检测来确定 COVID-19 感染的病史。从他们的医疗报告中收集人口统计学数据。通过面对面访谈收集眼部病史和眼部症状。在总共 308 名参与者中，264 名（85.7%）报告了 COVID-19 感染；73 名（27.65%）感染者在感染期间或之后抱怨各种眼部症状；只有 15 名（5.68%）感染者在康复后报告眼部症状。与封锁前相比，感染显著增加了眼红和眼痛的抱怨。在检查时，感染与非感染性感染之间在各种眼部检查中没有差异。感染发病日与检查日之间的持续时间与所有眼部检查均无关。COVID-19 感染可导致一些眼部症状，特别是在感染期的结膜充血和眼部疼痛，但在康复后约 1 个月内可能不会导致持续的眼部症状。本研究结果可能有助于缓解公众对冠状病毒感染眼部的担忧。然而，需要在多中心和社区人群中进行更大规模、具有多种冠状病毒感染的研究。
