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COVID-19 感染患者的结膜炎及其他眼部表现。

Conjunctivitis and other ocular findings in patients with COVID-19 infection.

机构信息

From the Department of Surgery, College of Medicine, University of Al Qadisiyah, Diwaniya, Qadisiyha, Iraq.

出版信息

Ann Saudi Med. 2021 Sep-Oct;41(5):280-284. doi: 10.5144/0256-4947.2021.280. Epub 2021 Oct 7.

Abstract

BACKGROUND

COVID-19 is an acute respiratory illness caused by a novel coronavirus (SARS-CoV-2). COVID-19 that might affect the eye in the form of conjunctivitis and other ocular features.

OBJECTIVES

Assess the frequency and clinical profile of conjunctivitis and other ocular findings in Iraqi patients with confirmed COVID-19 infection.

DESIGN

Analytical cross-sectional study.

SETTING

Secondary care center.

PATIENTS AND METHODS

This study involved patients diagnosed with SARS-CoV-2 viral infection of variable disease severity from June 2020 to December 2020. Ocular history and the severity of SARS-CoV-2 viral infection was assessed for all of the patients.

MAIN OUTCOME MEASURES

Frequency of conjunctival inflammation and other ocular findings in patients with coronavirus infection.

SAMPLE SIZE

186 patients.

RESULTS

The patients had a mean (standard deviation, range) age of 44.4 (18.8, 18-78) years. Conjunctivitis was present in 25 patients (13.4%). There was no significant association between prevalence of conjunctivitis and patient gender (=.868). However, conjunctivitis was significantly associated with the severity of the disease (=.018): the rate of conjunctivitis was significantly higher in cases with severe disease (28%) in comparison with those with mild to moderate clinical presentation (9.3%). The natural course of conjunctivitis seemed to be mild with no effect on visual acuity and no short-term complications.

CONCLUSION

Conjunctivitis can occur in patients with SARS-CoV-2 viral infection, and could be a presenting sign. Conjunctivitis is more common in cases of severe COVID-19 infection and since it could be a presenting sign it might be of benefit in the early diagnosis and treatment of COVID-19.

LIMITATION

Single-center study, safety limitations in the examination of the patients.

CONFLICT OF INTEREST

None.

摘要

背景

COVID-19 是一种由新型冠状病毒(SARS-CoV-2)引起的急性呼吸道疾病。COVID-19 可能以结膜炎和其他眼部特征的形式影响眼睛。

目的

评估伊拉克确诊 COVID-19 感染患者结膜炎和其他眼部表现的频率和临床特征。

设计

分析性横断面研究。

设置

二级保健中心。

患者和方法

本研究纳入了 2020 年 6 月至 2020 年 12 月间不同疾病严重程度的 SARS-CoV-2 病毒感染患者。对所有患者的眼部病史和 SARS-CoV-2 病毒感染的严重程度进行了评估。

主要观察指标

冠状病毒感染患者结膜炎症和其他眼部表现的频率。

样本量

186 例患者。

结果

患者的平均(标准差,范围)年龄为 44.4(18.8,18-78)岁。25 例(13.4%)患者出现结膜炎。结膜炎的患病率与患者性别无显著相关性(=.868)。然而,结膜炎与疾病严重程度显著相关(=.018):与轻度至中度临床表现的患者(9.3%)相比,严重疾病患者(28%)的结膜炎发生率显著更高。结膜炎的自然病程似乎较轻,对视力没有影响,也没有短期并发症。

结论

SARS-CoV-2 病毒感染患者可能会出现结膜炎,且可能为首发症状。结膜炎在严重 COVID-19 感染病例中更为常见,且由于它可能是首发症状,因此可能有助于 COVID-19 的早期诊断和治疗。

局限性

单中心研究,患者检查的安全性限制。

利益冲突

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3ca/8497005/b5e8ca8d72d0/asm-5-280.jpg

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