Jiangsu Province Key Laboratory for Fisheries Live Food, School of Marine Science and Engineering, Nanjing Normal University, No. 2 Xuelin Rd, Nanjing 210023, People's Republic of China.
Jiangsu Province Key Laboratory for Fisheries Live Food, School of Marine Science and Engineering, Nanjing Normal University, No. 2 Xuelin Rd, Nanjing 210023, People's Republic of China.
Mar Pollut Bull. 2024 Feb;199:115918. doi: 10.1016/j.marpolbul.2023.115918. Epub 2023 Dec 21.
Triclosan (TCS) poses an ecological health risk due to its lipophilic nature, long half-life, and bioconcentration. To evaluate the toxicity of TCS on aquatic organisms, the life history parameters, population dynamics, and transcriptome regulation of Brachionus plicatilis exposed to TCS were investigated. In this study, the fecundity of rotifers was promoted by 25 μg/L of TCS and inhibited by higher concentrations (100 μg/L, 200 μg/L). The reproductive period of rotifers was shortened by 46.24 % but the post-reproductive period was prolonged by 176.47 % in 200 μg/L TCS. Both population growth and life table parameters indicated that a high concentration of TCS (200 μg/L) had negative impacts on population growth. Transcriptomic analysis showed that the effects of TCS on the life history parameters and population dynamics of rotifers were determined by regulating the expression of functional genes in cilium organization and cilium assembly and involved in pathways of focal adhesion.
三氯生（TCS）由于其亲脂性、半衰期长和生物浓缩性，对生态健康构成风险。为了评估 TCS 对水生生物的毒性，研究了暴露于 TCS 的褶皱臂尾轮虫的生活史参数、种群动态和转录组调控。在这项研究中，25μg/L 的 TCS 促进了轮虫的繁殖力，而更高浓度（100μg/L、200μg/L）则抑制了繁殖力。TCS 浓度为 200μg/L 时，轮虫的生殖期缩短了 46.24%，但产后期延长了 176.47%。种群增长和生命表参数均表明，高浓度 TCS（200μg/L）对种群增长有负面影响。转录组分析表明，TCS 对轮虫生活史参数和种群动态的影响是通过调节纤毛组织和纤毛组装中功能基因的表达来确定的，这些基因参与了焦点黏附途径。
