Strupp Michael Leo, Zwergal Andreas, Goldschagg Nicolina
Neurologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Germany.
Deutsches Schwindel- und Gleichgewichtszentrum, DSGZ, Ludwig-Maximilians-Universität München, München, Germany.
Laryngorhinootologie. 2024 Mar;103(3):196-206. doi: 10.1055/a-2144-3801. Epub 2023 Dec 22.
Three forms of peripheral vestibular disorders, each with its typical symptoms and clinical signs, can be differentiated functionally, anatomically and pathophysiologically: 1. inadequate unilateral paroxysmal stimulation or rarely inhibition of the peripheral vestibular system, e. g., BPPV, Menière's disease, vestibular paroxysmia or syndrome of the third mobile windows; 2. acute unilateral vestibulopathy leading to an acute vestibular tone imbalance manifesting as an acute peripheral vestibular syndrome; and 3. loss or impairment of function of the vestibular nerve and/or labyrinth: bilateral vestibulopathy. For all of these diseases, current diagnostic criteria by the Bárány-Society are available with a high clinical and scientific impact, also for clinical trials. The treatment depends on the underlying disease. It basically consists of 5 principles: 1. Explaining the symptoms and signs, pathophysiology, aetiology and treatment options to the patient; this is important for compliance, adherence and persistence. 2. Physical therapy: A) For BPPV specific liberatory maneuvers, depending on canal involved. Posterior canal: The new SémontPLUS maneuver is superior to the regular Sémont and Epley maneuvers; horizontal canal: the modified roll-maneuver; anterior canal the modified Yacovino-maneuver; 3. Symptomatic or causative drug therapy. There is still a deficit of placebo-controlled clinical trials so that the level of evidence for pharmacotherapy is most often low. 4. Surgery, mainly for the syndrome of the third mobile windows. 5. Psychotherapeutic measures for secondary functional dizziness.
三种形式的外周前庭疾病,每种都有其典型症状和临床体征,可在功能、解剖和病理生理方面进行区分:1. 外周前庭系统单侧阵发性刺激不足或很少见的抑制,例如良性阵发性位置性眩晕(BPPV)、梅尼埃病、前庭阵发性症或第三活动窗综合征;2. 急性单侧前庭病导致急性前庭张力失衡,表现为急性外周前庭综合征;3. 前庭神经和/或迷路功能丧失或受损:双侧前庭病。对于所有这些疾病,巴兰尼协会的现行诊断标准具有很高的临床和科学影响力,对临床试验也是如此。治疗取决于潜在疾病。其基本包括5项原则:1. 向患者解释症状和体征、病理生理、病因及治疗选择;这对于依从性、坚持性很重要。2. 物理治疗:A)对于BPPV,根据受累半规管进行特定的复位手法。后半规管:新的SémontPLUS手法优于常规的Sémont和Epley手法;水平半规管:改良翻滚手法;前半规管:改良Yacovino手法;3. 对症或病因性药物治疗。安慰剂对照临床试验仍然不足,因此药物治疗的证据水平大多较低。4. 手术,主要针对第三活动窗综合征。5. 针对继发性功能性眩晕的心理治疗措施。