de Vries Esther, Uribe Claudia, Beltrán Rodríguez Claudia Catalina, Caparros Alfredo, Meza Erika, Gil Fabian
Department of Clinical Epidemiology and Biostatistics, Faculty of Medicina, Pontificia Universidad Javeriana, Ed. Hospital Universitario San Ignacio, Carrera 7 N° 40-62-piso 2, Bogotá 110231, Colombia.
Population Based Cancer Registry of Metropolitan Area of Bucaramanga, Universidad Autónoma de Bucaramanga, Calle 157 #14 55, Floridablanca 68276, Colombia.
Cancers (Basel). 2023 Dec 15;15(24):5848. doi: 10.3390/cancers15245848.
We aimed to improve the available information on morphology and stage for cutaneous melanoma in the population-based cancer registry of the Bucaramanga Metropolitan Area in Colombia. The incidence and survival rates and the distribution of melanoma patients by age, gender, anatomical subsite, and histological subtype were calculated. All 113 melanoma patients (median age 61) were followed up (median time 7.4 years). This exercise (filling in missing information in the registry by manual search of patient clinical record and other available information) yielded more identified invasive melanomas and cases with complete information on anatomical localization and stage. Age-standardized incidence and mortality rates were 1.86 and 1.08, being slightly higher for males. Most melanomas were localized on the lower limbs, followed by the trunk. For 35% of all melanomas, the morphological subtype remained unknown. Most of the remaining melanomas were nodular and acral lentiginous melanomas. Overall global and relative 5-year survival was 61.6% and 71.3%, respectively, with poorer survival for males than females. Melanomas on the head and neck and unspecified anatomical sites had the worst survival. Patients without stage information in their medical files had excellent survival, unlike patients for whom medical files were no longer available. This study shows the possibility of improving data availability and the importance of good quality population-based data.
我们旨在完善哥伦比亚布卡拉曼加都会区基于人群的癌症登记处中皮肤黑色素瘤的形态学和分期方面的现有信息。计算了黑色素瘤患者的发病率、生存率以及按年龄、性别、解剖亚部位和组织学亚型划分的分布情况。对所有113例黑色素瘤患者(中位年龄61岁)进行了随访(中位时间7.4年)。这项工作(通过人工查阅患者临床记录和其他可用信息来填补登记处缺失的信息)发现了更多确诊的侵袭性黑色素瘤病例以及解剖定位和分期信息完整的病例。年龄标准化发病率和死亡率分别为1.86和1.08,男性略高。大多数黑色素瘤位于下肢,其次是躯干。35%的黑色素瘤病例形态学亚型仍不明。其余大多数黑色素瘤为结节型和肢端雀斑样黑色素瘤。总体5年总生存率和相对生存率分别为61.6%和71.3%,男性生存率低于女性。头颈部及解剖部位未明确的黑色素瘤患者生存率最差。病历中无分期信息的患者生存率良好,与病历不再可用的患者情况不同。本研究表明了改善数据可用性的可能性以及高质量基于人群的数据的重要性。