Merino-Andrés Javier, Pérez-Nombela Soraya, Hidalgo-Robles Álvaro, Pérez-Domínguez María Del Prado, Prieto-Sánchez Lorena, Fernández-Rego Francisco Javier
Faculty of Physiotherapy and Nursing, Universidad de Castilla-La Mancha, Avenida de Carlos III s/n, 45071 Toledo, Spain.
Physiotherapy Research Group of Toledo (GIFTO), Universidad de Castilla-La Mancha, Avenida de Carlos III s/n, 45071 Toledo, Spain.
J Clin Med. 2023 Dec 18;12(24):7763. doi: 10.3390/jcm12247763.
Moderate-late preterm infants constitute the largest segment of preterm births globally. While previously considered to have a low neurological risk, recent research has uncovered an elevated incidence of neurodevelopmental conditions in this group. This study aimed to assess the relationship between the general movement assessment and birth-related risk factor-based tools in moderate-late preterm infants.
A prospective cohort study of 65 moderate-late preterm infants in a neonatal intensive care unit involved the evaluation of general movements, the Nursery Neurobiologic Risk Score, and the Perinatal Risk Inventory. Associations were analyzed using Fisher's exact test, Spearman's correlation was used for ordinal variables, and backward stepwise logistic regression was used to identify predictor variables for the assessments.
The findings indicated a high prevalence of normal (41%) and poor (52%) repertoire patterns during the writhing period. While no significant associations were found between the three assessments, a slight approximation emerged between dysmorphic traits and patterns ( = 0.053). Furthermore, an extended period of ventilation correlated with a higher likelihood of developing a cramped synchronized pattern and there was a correlation between both risk factor-based tools ( < 0.001).
This research enhances our understanding of the early impact on general movement assessments in moderate-late preterm infants. While no clear relationship emerged between general movement assessment and risk factor-based tools, there was a subtle connection noted with dysmorphic traits. A longer ventilation duration was linked to a higher risk of developing cramped synchronized patterns.
中晚期早产儿是全球早产婴儿中数量最多的群体。虽然此前认为该群体的神经风险较低,但最近的研究发现这一群体中神经发育疾病的发病率有所上升。本研究旨在评估中晚期早产儿的全身运动评估与基于出生相关风险因素的工具之间的关系。
对一家新生儿重症监护病房的65名中晚期早产儿进行了一项前瞻性队列研究,涉及全身运动评估、新生儿神经生物学风险评分和围产期风险清单。使用Fisher精确检验分析关联,对有序变量使用Spearman相关性分析,并使用向后逐步逻辑回归来确定评估的预测变量。
研究结果表明,在扭动期,正常(41%)和不良(52%)的动作模式普遍存在。虽然在三项评估之间未发现显著关联,但畸形特征与动作模式之间出现了轻微的近似关系(P = 0.053)。此外,通气时间延长与出现痉挛同步模式的可能性增加相关,并且两种基于风险因素的工具之间存在相关性(P < 0.001)。
本研究增进了我们对中晚期早产儿全身运动评估早期影响的理解。虽然全身运动评估与基于风险因素的工具之间未出现明确关系,但与畸形特征存在细微联系。通气持续时间较长与出现痉挛同步模式的风险较高相关。