Hines Lauren N, King Jacob R, Atwood Alex C, Chapman Rachel M, Griffey Matthew B, Tutwiler Christine R, Monceaux Christopher Jon
Department of Chemistry, Radford University, Radford, VA 24142, USA.
Molecules. 2023 Dec 6;28(24):7968. doi: 10.3390/molecules28247968.
Herein we describe a novel route to indole derivatives from a variety of -substituted 2-alkenylanilines. This route features three operationally simple steps: (1) oxidation to convert -substituted 2-alkenylanilines into epoxide intermediates, (2) intramolecular cyclization, and (3) the acid-catalyzed elimination of water.
在此，我们描述了一种从多种α-取代的2-烯基苯胺制备吲哚衍生物的新方法。该方法具有三个操作简单的步骤：（1）氧化，将α-取代的2-烯基苯胺转化为环氧化合物中间体；（2）分子内环化；（3）酸催化脱水。
