感染 SARS-CoV-2 后儿童对抗原性先进的奥密克戎 BA.5 的中和免疫。
Neutralizing Immunity Against Antigenically Advanced Omicron BA.5 in Children After SARS-CoV-2 Infection.
机构信息
Center for Clinical Epidemiology and Population Health, Marshfield Clinic Research Institute, Marshfield, Wisconsin, USA.
Coronavirus and Other Respiratory Viruses Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
出版信息
J Pediatric Infect Dis Soc. 2024 Jan 29;13(1):100-104. doi: 10.1093/jpids/piad109.
We assessed serum neutralization of Omicron BA.5 in children following SARS-CoV-2 infection during the Delta or Omicron BA.1/BA.2 variant period. Convalescent BA.5 titers were higher following infections during the Omicron BA.1/BA.2 vs Delta variant period, and in vaccinated vs unvaccinated children. Titers against BA.5 did not differ by age group.
我们评估了在 Delta 或 Omicron BA.1/BA.2 变异株流行期间感染 SARS-CoV-2 的儿童血清对 Omicron BA.5 的中和作用。与 Delta 变异株流行期间相比，Omicron BA.1/BA.2 流行期间感染后 BA.5 的恢复期滴度更高，且在接种疫苗和未接种疫苗的儿童中也是如此。针对 BA.5 的滴度与年龄组无关。
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