Anti- Evaluation of Sponge-Associated Bacteria on the Survival Rate of Infected with Pathogenic Species.

Sponge-associated bacteria are considered a rich source of bioactive compounds particularly to reduce the risk of and infection. The present study aimed to analyse the effectiveness of 19 isolates to control infection . All 19 isolates displayed a non-pathogenic characteristic on shrimps (cell density of 10 cells/mL) as analysed using the pathogenicity test. The mortality caused by both spp. on 50% of the shrimp population (LC value) had a cell density of 10 cells/mL as determined using the proportion interval method. On the basis of the challenge test, all isolates improved the survival rate of infected shrimps in diverse effectivities up to 89%, which was nearly 30% higher than the infected control. Two isolates coded as D6.9, and P5.20 reduced shrimp mortality after infection with spp. 16S rRNA-based identification showed these isolates were closely similar to different genera of and . The extract derived from the most prospective isolate, D6.9, was dominated by 1-hydroxy-6-(3-isopropenyl-cycloprop-1-enyl)-6-methyl-heptan-2-one, hexadecanoic acid, 4-epicyclomusalenone [(24S)-24-methyl-28-norcycloart-25-en-3-one], and 2,4-dimethyl acetoacetanilide. This observation suggested these isolates characterised by anti- activity need to be further developed as biocontrol candidates.