Lee Sun Jung, Jang Tae Su, Kim Jae Kyung
Department of Biomedical Laboratory Science, Dankook University College of Health Sciences, Chungnam, Republic of Korea.
Department of Health Administration, Dankook University College of Health Sciences, Chungnam, Republic of Korea.
Ther Adv Infect Dis. 2023 Dec 21;10:20499361231220154. doi: 10.1177/20499361231220154. eCollection 2023 Jan-Dec.
The prevalence of sexually transmitted infections (STIs) remains high worldwide. Despite the worldwide increase in the incidence of STIs every year, there are few reports on the frequency of STIs with different pathogens according to age and gender. Accordingly, a study was conducted to determine trends in co-infection with STIs by age and gender in Cheonan, South Korea from 2017 to 2021.
To identify trends by age or sex in co-infection of STIs in this region.
A retrospective study was conducted on clinical samples examined at Dankook University Hospital from January 2017 to November 2021. A total of 3297 specimens were collected from patients visiting Dankook University Hospital (Cheonan, Korea), and statistical analysis was performed on patients ranging in age from 1 day to 93 years.
Multiplex polymerase chain reaction, the most efficient method to diagnose a bacterial infection, was performed using an MJ Research PTC-200 Thermal Cycler (Marshall Scientific, Richmond, VA, USA) and a Seeplex STD Detection Kit (Seegene, Seoul, Republic of Korea). The co-infection rate with STI pathogens was analyzed according to age and sex.
Of the 3297 clinical samples, 1017 (30.9%) tested positive for sexually transmitted pathogens, ranging from one to six co-infections. Analysis of the co-infection rate by age revealed that the average age gradually decreased as the total number of co-infection pathogens increased. The co-infection percentage and age distribution of STIs differed according to sex. Co-infection was more prevalent in female patients. Furthermore, co-infection in male patients occurred frequently in the 30-39-year-old group, while those in female patients occurred in the 20-29- and 30-39-year-old groups.
Our statistical analysis showed that STI co-infections were more common among younger than older people. Therefore, it helps in recognizing STIs at a young age and provides possible indicator data to prevent STIs at a young age. In addition, further research is needed on co-infection in other regions.
性传播感染（STIs）在全球的患病率仍然很高。尽管全球每年性传播感染的发病率都在上升，但关于不同病原体性传播感染按年龄和性别的发病频率的报道却很少。因此，开展了一项研究以确定2017年至2021年韩国天安地区性传播感染合并感染按年龄和性别的趋势。
确定该地区性传播感染合并感染按年龄或性别的趋势。
对2017年1月至2021年11月在韩国檀国大学医院检查的临床样本进行回顾性研究。共从访问韩国檀国大学医院（天安）的患者中收集了3297份样本，并对年龄在1天至93岁之间的患者进行了统计分析。
使用MJ Research PTC - 200热循环仪（Marshall Scientific，美国弗吉尼亚州里士满）和Seeplex STD检测试剂盒（Seegene，韩国首尔）进行多重聚合酶链反应，这是诊断细菌感染最有效的方法。根据年龄和性别分析性传播感染病原体的合并感染率。
在3297份临床样本中，1017份（30.9%）性传播病原体检测呈阳性，合并感染病原体数量从1种到6种不等。按年龄分析合并感染率发现，随着合并感染病原体总数的增加，平均年龄逐渐降低。性传播感染的合并感染百分比和年龄分布因性别而异。合并感染在女性患者中更为普遍。此外，男性患者的合并感染在30 - 39岁年龄组中频繁发生，而女性患者的合并感染则发生在20 - 29岁和30 - 39岁年龄组中。
我们的统计分析表明，性传播感染合并感染在年轻人中比在老年人中更常见。因此，这有助于在年轻时识别性传播感染，并为预防年轻人中的性传播感染提供可能的指标数据。此外，还需要对其他地区的合并感染进行进一步研究。
