Andreev A Iu, Iaguzhinskiĭ L S
Nauchnye Doki Vyss Shkoly Biol Nauki. 1986(11):16-25.
The chemical language of genetic code is proposed. As a result of chemical language application for the analysis of the modern genetic code, the existence of an unambiguous correspondence between the chemical properties of amino acids and their coding triplets (codons and anticodons) is shown. This confirms the hypothesis of the code chemical determination. The complementarity between the chemical properties of amino acids and their anticodons (but not the codons) has been found also to exist. This observation supports the hypothesis of the genetic code determination by the direct recognition and also underlines the primary role of anticodon in the origin of genetic code in comparison with codons.
提出了遗传密码的化学语言。通过将化学语言应用于现代遗传密码的分析,表明氨基酸的化学性质与其编码三联体(密码子和反密码子)之间存在明确的对应关系。这证实了密码化学决定的假说。还发现氨基酸与其反密码子(而非密码子)的化学性质之间存在互补性。这一观察结果支持了通过直接识别来确定遗传密码的假说,并且强调了与密码子相比,反密码子在遗传密码起源中的主要作用。