女性阻塞性睡眠呼吸暂停与膀胱疼痛综合征/间质性膀胱炎
Obstructive sleep apnea and bladder pain syndrome/interstitial cystitis in women.
作者信息
Çoşğun İbrahim Güven, Gürel Abdullah
机构信息
Department of Pulmonology, Afyonkarahisar Health Sciences University Medical Faculty, Afyonkarahisar, Turkey.
Department of Urology, Afyonkarahisar Health Sciences University Medical Faculty, Afyonkarahisar, Turkey.
出版信息
Sleep Breath. 2024 May;28(2):999-1003. doi: 10.1007/s11325-023-02967-1. Epub 2023 Dec 26.
PURPOSE
The relationship between obstructive sleep apnea (OSA) and bladder pain syndrome/interstitial cystitis (BPS/IC) remains uncertain. Therefore, this study aimed to compare the frequency of BPS/IC seen in women diagnosed with OSA and in women without OSA.
MATERIAL AND METHODS
The study included a patient group of women with OSA and a control group of women without OSA. All the study participants were administered the Berlin Questionnaire, Epworth Sleepiness Scale, Interstitial Cystitis Symptom Index (ICSI), and the Interstitial Cystitis Problem Index (ICPI). Differences between the women with OSA and the control group were examined.
RESULTS
The study sample consisted of 46 women with OSA and 46 controls. No significant difference was determined between the OSA and control groups concerning age and body mass index (p = 0.810, p = 0.060, respectively). The ESS was greater in the OSA group than in the control group (p = 0.007). The median (IQR) ICSI was 8 (4-11.25) in women with OSA and 5 (1.75-7.15) in controls (p < 0.001). The median (IQR) ICPI was 7 (6.00-10.25) in women with OSA and 6 (1.75-8.00) in controls (p < 0.001). CONCLUSIONS: The ICSI symptoms and subsequent problems in daily life caused by the symptoms (ICPI) were experienced at a higher rate in patients with OSA than in the control group. There is an association between BPS/IC and OSA.
目的
阻塞性睡眠呼吸暂停（OSA）与膀胱疼痛综合征/间质性膀胱炎（BPS/IC）之间的关系仍不明确。因此，本研究旨在比较被诊断为OSA的女性和未患OSA的女性中BPS/IC的发病频率。
材料与方法
该研究包括一组患有OSA的女性患者和一组未患OSA的女性对照组。所有研究参与者均接受了柏林问卷、爱泼华嗜睡量表、间质性膀胱炎症状指数（ICSI）和间质性膀胱炎问题指数（ICPI）的评估。对患有OSA的女性和对照组之间的差异进行了检查。
结果
研究样本包括46名患有OSA的女性和46名对照组女性。OSA组和对照组在年龄和体重指数方面未发现显著差异（分别为p = 0.810，p = 0.060）。OSA组的ESS高于对照组（p = 0.007）。患有OSA的女性的ICSI中位数（IQR）为8（4 - 11.25），对照组为5（1.75 - 7.15）（p < 0.001）。患有OSA的女性的ICPI中位数（IQR）为7（6.00 - 10.25），对照组为6（1.75 - 8.00）（p < 0.001）。结论：OSA患者出现ICSI症状及这些症状在日常生活中引发的后续问题（ICPI）的比例高于对照组。BPS/IC与OSA之间存在关联。
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