Runwal Gautam M, Edwards Robert H
Departments of Neurology and Physiology, UCSF School of Medicine, United States of America; Departments of Neurology and Physiology, UCSF School of Medicine, United States of America- Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815, United States of America.
Departments of Neurology and Physiology, UCSF School of Medicine, United States of America; Departments of Neurology and Physiology, UCSF School of Medicine, United States of America- Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD 20815, United States of America.
Exp Neurol. 2024 Mar;373:114668. doi: 10.1016/j.expneurol.2023.114668. Epub 2023 Dec 24.
The pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein α-synuclein (αsyn). αSyn has been shown to regulate several cellular processes, however, its normal function remains poorly understood. In this review, we will specifically focus on its role in exocytosis.
帕金森病（PD）退变的发病机制仍知之甚少，但多条证据均指向突触前蛋白α-突触核蛋白（αsyn）。αSyn已被证明可调节多种细胞过程，然而，其正常功能仍知之甚少。在本综述中，我们将特别关注其在胞吐作用中的作用。
