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[感染诱导的固有免疫反应研究进展]

[Advances in innate immune responses induced by infection].

作者信息

Lai Jiacui, He Jiawei, Ding Honglei

机构信息

Laboratory of Veterinary Mycoplasmology, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2023 Dec 25;39(12):4773-4783. doi: 10.13345/j.cjb.230504.

DOI:10.13345/j.cjb.230504
PMID:38147980
Abstract

is the pathogen causing swine mycoplasmal pneumonia. The lack of well-established animal models of . infection has delayed the progress of . -related anti-infection immunity studies. This paper reviews the inflammatory response, the recognition of . by the innate immune system, and the role of innate immune cells, complement system, antimicrobial peptides, autophagy, and apoptosis in . infection. The aim was to elucidate the important roles played by the components of the innate immune system in the control of . infection, and prospect key research directions of innate immune response of . infection in the future.

摘要

是引起猪支原体肺炎的病原体。缺乏完善的动物感染模型延缓了与……感染相关的抗感染免疫研究的进展。本文综述了炎症反应、固有免疫系统对……的识别,以及固有免疫细胞、补体系统、抗菌肽、自噬和凋亡在……感染中的作用。目的是阐明固有免疫系统各组分在控制……感染中发挥的重要作用,并展望未来……感染固有免疫反应的关键研究方向。

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