Cardiology Department, Hospital de Santa Cruz, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Comprehensive Health Research Centre, NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal.
J Int Med Res. 2023 Dec;51(12):3000605231218645. doi: 10.1177/03000605231218645.
The mitral valve apparatus is a complex structure consisting of several coordinating components: the , two leaflets, the and the papillary muscles. Due to the intricate interplay between the mitral valve and the left ventricle, a disease of the latter may influence the normal function of the former. As a consequence, valve insufficiency may arise despite the absence of organic valve disease. This is designated as functional or secondary mitral regurgitation, and it arises from a series of distortions to the valve components. This narrative review describes the normal anatomy and the pathophysiology behind the mitral valve changes in ischemic and non-ischemic dilated cardiomyopathies. It also explains the value of a complete multiparametric assessment of this structure. Not only must an assessment include quantitative measures of regurgitation, but also various anatomical parameters from the mitral apparatus and left ventricle, since they carry prognostic value and are predictors of mitral valve repair success and durability.
二尖瓣装置是一个复杂的结构,由几个协调的组成部分组成:, 两个瓣叶, 和乳头肌。由于二尖瓣和左心室之间的复杂相互作用,后者的疾病可能会影响前者的正常功能。因此,尽管没有器质性瓣膜疾病,也可能会出现瓣膜关闭不全。这种情况被指定为功能性或继发性二尖瓣反流,它是由于瓣膜成分的一系列扭曲引起的。这篇叙述性综述描述了缺血性和非缺血性扩张型心肌病中二尖瓣变化背后的正常解剖结构和病理生理学。它还解释了对该结构进行完整的多参数评估的价值。评估不仅必须包括反流的定量测量,还必须包括二尖瓣装置和左心室的各种解剖参数,因为它们具有预后价值,并且是二尖瓣修复成功和耐久性的预测指标。