Wang Yindian, Xu Chengcheng, Zhou Yangyang, Lee Jaebeom, Chen Qiang, Chen Hongxia
School of Medicine, Shanghai University, Shanghai, 200444, P. R. China.
School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, P. R. China.
Small. 2024 Jun;20(23):e2308897. doi: 10.1002/smll.202308897. Epub 2023 Dec 27.
MXene is widely used in the construction of optoelectronic interfaces due to its excellent properties. However, the hydrophilicity and metastable surface of MXene lead to its oxidation behavior, resulting in the degradation of its various properties, which seriously limits its practical application. In this work, a 2D metal-organic framework (2D MOF) with matching 2D morphology, excellent stability performance, and outstanding optoelectronic performance is grown in situ on the MXene surface through heterojunction engineering to suppress the direct contact between reactive molecules and the inner layer material without affecting the original advantages of MXene. The photoelectric dual gain MXene@MOF heterojunction is confirmed. As a photoelectric material, its properties are highly suitable for the demand of interface sensitization layer materials of surface plasmon resonance (SPR). Therefore, using SPR as a platform for the application of this interface material, the performance of MXene@MOF and its potential mechanism to enhance SPR are analyzed in depth using experiments combined with simulation calculations (FDTD/DFT). Finally, the MXene@MOF/peptides-SPR sensor is constructed for rapid and sensitive detection of the cancer marker exosomes to explore its potential in practical applications. This work offers a forward-looking strategy for the design of interface materials with excellent photoelectric performance.
MXene因其优异的性能而被广泛应用于光电界面的构建。然而，MXene的亲水性和亚稳表面导致其氧化行为，从而使其各种性能退化，这严重限制了其实际应用。在这项工作中，通过异质结工程在MXene表面原位生长了一种具有匹配二维形态、优异稳定性和出色光电性能的二维金属有机框架（2D MOF），以抑制反应性分子与内层材料的直接接触，同时不影响MXene的原有优势。证实了光电双增益的MXene@MOF异质结。作为一种光电材料，其性能高度适合表面等离子体共振（SPR）界面敏化层材料的需求。因此，以SPR作为该界面材料的应用平台，结合实验和模拟计算（FDTD/DFT）深入分析了MXene@MOF的性能及其增强SPR的潜在机制。最后，构建了MXene@MOF/肽-SPR传感器用于快速灵敏地检测癌症标志物外泌体，以探索其在实际应用中的潜力。这项工作为设计具有优异光电性能的界面材料提供了一种前瞻性策略。
