Zerr C, Roland E, Lebreton P, Fauchon G, Renouf P, Nivaud M, Khayat A
Cah Anesthesiol. 1986 Nov;34(7):573-9.
The effects of recuperation from the remaining pump circuit blood with restitution to the patient after hemoconcentration are studied in 80 patients undergoing cardiopulmonary by-pass. This population is randomized into two groups: group 1 of 41 patients represents the control group and is compared with the group 2 of 39 patients who undergo the post-by-pass hemoconcentration. The volume of restored blood is 669 +/- 14 ml with an hematocrit of 38 +/- 6,6% and the total protein concentration is 81,2 +/- 2 g.l-1. The heparin level is high (4,24 units.ml-i) and the perfusion of the hemoconcentrated blood must be preceded by a slow injection of 0,8 mg.kg-1 of protamine sulfate. The advantages of this method represent a saving of two homologous blood units (p less than or equal to 10(-4] and the post operative urine output is increased by 32% (p less than or equal to 0,05). No complication, particularly infectious, was observed in this study.
对80例接受体外循环的患者进行了研究，观察血液浓缩后将剩余泵回路血液回输至患者体内的恢复效果。该人群被随机分为两组：41例患者的第1组为对照组，与39例接受体外循环后血液浓缩的第2组进行比较。回输血液的体积为669±14 ml，血细胞比容为38±6.6%，总蛋白浓度为81.2±2 g·l-1。肝素水平较高（4.24单位·ml-1），在回输浓缩血液前必须缓慢注射0.8 mg·kg-1硫酸鱼精蛋白。该方法的优点是节省了两个同源血单位（p≤10-4），术后尿量增加了32%（p≤0.05）。本研究未观察到并发症，尤其是感染性并发症。
