Paulsen H, Peters T, Sinnwell V, Heume M, Meyer B
Carbohydr Res. 1986 Nov 15;156:87-106. doi: 10.1016/s0008-6215(00)90102-2.
In the conformational analysis of the pentasaccharide alpha-D-Manp-(1----3)-[beta-D-GlcpNAc-(1----4)]-[alpha-D- Manp-(1----6)]-beta-D-Manp-(1----4)-D-GlcNAc, which represents the essential core structure within the bisected type of N-glycoproteins, n.m.r. experiments and GESA calculations indicated that a gg conformation is preferred for the (1----6)-glycosidic linkage. This is in contrast to the results obtained for the tetrasaccharide alpha-D-Manp-(1----3)-[alpha-D-Manp-(1----6)]-beta-D- Manp-(1----4)- D-GlcNAc, which indicated that a gt conformation with the (1----6)-linked alpha-D-mannose group folded back is preferred. The conformations of the remaining glycosidic linkages in the tetra- and penta-saccharide are similar.
在五糖α-D-甘露糖基-（1→3）-[β-D-乙酰氨基葡萄糖基-（1→4）]-[α-D-甘露糖基-（1→6）]-β-D-甘露糖基-（1→4）-D-乙酰氨基葡萄糖的构象分析中，该五糖代表了双叉型N-糖蛋白的基本核心结构，核磁共振实验和GESA计算表明，（1→6）-糖苷键更倾向于gg构象。这与四糖α-D-甘露糖基-（1→3）-[α-D-甘露糖基-（1→6）]-β-D-甘露糖基-（1→4）-D-乙酰氨基葡萄糖的结果相反，后者表明（1→6）连接的α-D-甘露糖基团向后折叠的gt构象更受青睐。四糖和五糖中其余糖苷键的构象相似。
