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BMJ Case Rep. 2023 Dec 28;16(12):e256766. doi: 10.1136/bcr-2023-256766.
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本文引用的文献

1
WHO's Global Tuberculosis Report 2022.世界卫生组织《2022年全球结核病报告》。
Lancet Microbe. 2023 Jan;4(1):e20. doi: 10.1016/S2666-5247(22)00359-7. Epub 2022 Dec 12.
2
First vaccination after birth: serious adverse events of Bacillus Calmette-Guérin (BCG) in real-world.出生后首次接种疫苗:卡介苗(BCG)在真实世界中的严重不良事件。
Hum Vaccin Immunother. 2022 Nov 30;18(5):2080443. doi: 10.1080/21645515.2022.2080443. Epub 2022 Jun 10.
3
Outcome of inadvertent high dose BCG administration in newborns at a tertiary care hospital, Karachi- Case series.卡拉奇一家三级护理医院新生儿意外大剂量卡介苗接种的结果-病例系列。
PLoS One. 2019 Jul 10;14(7):e0219324. doi: 10.1371/journal.pone.0219324. eCollection 2019.
4
BCG vaccine: WHO position paper, February 2018 - Recommendations.BCG 疫苗:世卫组织立场文件,2018 年 2 月-建议。
Vaccine. 2018 Jun 7;36(24):3408-3410. doi: 10.1016/j.vaccine.2018.03.009. Epub 2018 Mar 30.
5
The management and outcome of Bacillus Calmette-Guérin vaccine overdose.卡介苗过量接种的管理与结局
Pediatr Neonatol. 2018 Apr;59(2):208-210. doi: 10.1016/j.pedneo.2017.07.004. Epub 2017 Aug 2.
6
The Adverse Events, Signs, and Management of Neonatal Bacillus Calmette-Guérin Vaccine Overdose.新生儿卡介苗过量的不良事件、体征及处理
Oman Med J. 2016 Jul;31(4):315-7. doi: 10.5001/omj.2016.61.
7
Adverse reactions to the Bacillus Calmette-Guérin (BCG) vaccine in new-born infants-an evaluation of the Danish strain 1331 SSI in a randomized clinical trial.新生儿对卡介苗(BCG)疫苗的不良反应——一项关于丹麦1331株SSI菌株的随机临床试验评估
Vaccine. 2016 May 11;34(22):2477-82. doi: 10.1016/j.vaccine.2016.03.100. Epub 2016 Apr 7.
8
Scar formation and tuberculin conversion following BCG vaccination in infants: A prospective cohort study.婴儿接种卡介苗后的瘢痕形成与结核菌素转化:一项前瞻性队列研究。
J Family Med Prim Care. 2015 Jul-Sep;4(3):384-7. doi: 10.4103/2249-4863.161327.
9
Management and outcome of Bacille Calmette-Guérin vaccine adverse reactions.卡介苗不良反应的管理与结局
Vaccine. 2015 Oct 5;33(41):5470-5474. doi: 10.1016/j.vaccine.2015.07.103. Epub 2015 Aug 12.
10
Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis.卡介苗接种对儿童结核分枝杆菌感染的影响:系统评价与荟萃分析
BMJ. 2014 Aug 5;349:g4643. doi: 10.1136/bmj.g4643.

新生儿双卡介苗接种:影响、管理和预防。

Double BCG vaccination in a neonate: implications, management and prevention.

机构信息

Neonatology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Neonatology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India

出版信息

BMJ Case Rep. 2023 Dec 28;16(12):e256766. doi: 10.1136/bcr-2023-256766.

DOI:10.1136/bcr-2023-256766
PMID:38154875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10759019/
Abstract

Tuberculosis is a common cause of morbidity and mortality especially in low-income and middle-income countries like India. BCG vaccination is recommended for all neonates after birth in areas with a high tuberculosis disease burden. Here, we describe a case where a neonate received two doses of the BCG (Chennai strain) vaccine within a span of 4 days after birth due to a vaccination error. Parents were informed about the event. The infant was managed conservatively and followed up till 12 months of life for any possible complication. There were no serious adverse effects apart from the localised reaction and a double scar on the left arm. Measures to avoid any such error in the future and the need for reporting medication error has been highlighted. Parental concerns are frequent in such scenarios and should be actively addressed.

摘要

结核病是发病率和死亡率的一个常见原因,特别是在印度等低收入和中等收入国家。在结核病负担高的地区,建议所有新生儿在出生后接种卡介苗。在这里,我们描述了一个新生儿由于接种错误,在出生后 4 天内接受了两剂卡介苗(Chennai 株)疫苗的情况。告知了家长这一事件。对婴儿进行了保守治疗,并在 12 个月大时进行随访,以观察任何可能的并发症。除了左臂局部反应和双重疤痕外,没有出现严重的不良反应。强调了避免未来发生此类错误和报告药物错误的必要性。在这种情况下,家长经常会担心,应积极解决。