Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University Health System, Virginia Commonwealth University School of Dentistry, Richmond, VA, USA; Department of Surgical Sciences, College of Dentistry, Health Sciences Center, Kuwait University, Jabriya, Kuwait.
Department of Oral and Maxillofacial Surgery, Virginia Commonwealth University Health System, Virginia Commonwealth University School of Dentistry, Richmond, VA, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2024 Apr;137(4):e53-e56. doi: 10.1016/j.oooo.2023.09.005. Epub 2023 Sep 27.
Peripheral ameloblastoma (PA) is a rare variant of ameloblastoma that presents as a slow-growing, painless mass in the gingival tissues or alveolar mucosa. It shares histologic features with conventional ameloblastoma but is less invasive and aggressive. This case report describes a 51-year-old female with a PA that simultaneously or subsequently developed underlying squamous cell papilloma after mandibular third molar extraction. Clinical examination revealed a pedunculated gingival lesion mimicking squamous cell papilloma. Histopathologic examination confirmed PA underlying squamous cell papilloma after an excisional biopsy. Imaging revealed mild bone resorption, leading to a further soft tissue excision and minimal osteoectomy to rule out intraosseous involvement. The patient remained asymptomatic without signs of recurrence in the 1-year follow-up. PA diagnosis can be challenging due to its clinical resemblance to other gingival lesions and histopathologic features. Treatment typically involves surgical excision, with long-term follow-up recommended due to possible recurrence and malignant transformation.
外周型成釉细胞瘤（PA）是成釉细胞瘤的一种罕见变异型，表现为牙龈组织或牙槽黏膜中缓慢生长、无痛的肿块。它具有与常规成釉细胞瘤相同的组织学特征，但侵袭性和侵袭性较低。本病例报告描述了一名 51 岁女性，在下颌第三磨牙拔除后同时或随后发生了 PA 伴发的鳞状细胞乳头状瘤。临床检查显示一个带蒂的牙龈病变，类似于鳞状细胞乳头状瘤。组织病理学检查在切除活检后证实为 PA 伴发鳞状细胞乳头状瘤。影像学显示轻度骨质吸收，进一步进行软组织切除和最小程度的骨切除术，以排除骨内受累。患者在 1 年的随访中无任何症状，无复发迹象。PA 的诊断具有挑战性，因为其临床表现类似于其他牙龈病变，且组织病理学特征也不具特异性。治疗通常采用手术切除，由于可能复发和恶性转化，建议长期随访。
