National Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
National Clinical Research Center for Geriatrics, and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
Virol Sin. 2024 Apr;39(2):331-334. doi: 10.1016/j.virs.2023.12.006. Epub 2023 Dec 28.
• Phospholipid-binding abilities of mpox virus A7 protein and its truncations are investigated. • The structures of the N-terminal truncations of A7 protein (A7N and A7N) are determined. • Conformational changes of the conserved linking helix in A7 are illustrated. • A structural model of the full-length A7 protein is proposed.
• 研究了猴痘病毒 A7 蛋白及其截短体与磷脂的结合能力。 • 测定了 A7 蛋白 N 端截短体（A7N 和 A7N）的结构。 • 说明了 A7 中保守连接螺旋的构象变化。 • 提出了全长 A7 蛋白的结构模型。
