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香港一家三级转诊中心对先天性膈疝的开放式与胸腔镜修复术:19 年回顾。

Open Versus Thoracoscopic Repair of Congenital Diaphragmatic Hernia: A 19-Year Review in a Tertiary Referral Centre in Hong Kong.

机构信息

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Hong Kong, China; Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, 2050, Australia.

Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Hong Kong, China.

出版信息

J Pediatr Surg. 2024 Apr;59(4):583-586. doi: 10.1016/j.jpedsurg.2023.12.011. Epub 2023 Dec 9.

Abstract

BACKGROUND

Congenital diaphragmatic hernia (CDH) is a developmental defect that causes herniation of abdominal organs into the thoracic cavity with significant morbidity. Thoracoscopic repair of CDH is an increasingly prevalent yet controversial surgical technique, with limited long-term outcome data in the Asian region. The aim of this study was to compare open laparotomy versus thoracoscopic repair of CDH in paediatric patients in a major tertiary referral centre in Asia.

METHODS

We performed a retrospective analysis of neonatal patients who had open laparotomy or thoracoscopic repair for CDH in our institution between July 2002 and November 2021. Demographic data, perioperative parameters, recurrence rates and surgical complications were analysed.

RESULTS

64 patients were identified, with 54 left sided CDH cases. 33 patients had a prenatal diagnosis and 35 patients received minimally invasive surgical repair. There was no significant difference between open and minimally invasive repair in recurrence rate (13 % vs 17 %, P = 0.713), time to recurrence (184 ± 449 days vs 81 ± 383 days, P = 0.502), or median length of ICU stay (11 ± 14 days vs 13 ± 15 days, P = 0.343), respectively. Gastrointestinal complications occurred in 7 % of neonates in the open group and none in the thoracoscopic group. Median follow-up time was 9.5 years.

CONCLUSIONS

This study is a large congenital diaphragmatic hernia series in Asia, with long term follow-up demonstrating no significant difference in recurrence rate, time to recurrence or median length of ICU stay between open and minimally invasive repair, suggesting thoracoscopic approach is a non-inferior surgical option with avoidance of gastrointestinal complications compared to open repair.

TYPE OF STUDY

Retrospective Cohort Study.

摘要

背景

先天性膈疝 (CDH) 是一种发育缺陷,导致腹部器官疝入胸腔,发病率较高。胸腔镜修复 CDH 是一种越来越流行但有争议的手术技术,在亚洲地区的长期结果数据有限。本研究旨在比较亚洲一家主要三级转诊中心的开腹手术与胸腔镜修复 CDH 的疗效。

方法

我们对 2002 年 7 月至 2021 年 11 月期间在我院接受开腹或胸腔镜治疗 CDH 的新生儿患者进行了回顾性分析。分析了人口统计学数据、围手术期参数、复发率和手术并发症。

结果

共纳入 64 例患者,其中 54 例为左侧 CDH 病例。33 例患者有产前诊断,35 例患者接受微创外科治疗。开腹组和微创组的复发率(13% vs 17%,P=0.713)、复发时间(184±449 天 vs 81±383 天,P=0.502)或 ICU 住院中位数(11±14 天 vs 13±15 天,P=0.343)均无显著差异。开腹组 7%的新生儿出现胃肠道并发症,而胸腔镜组无一例发生。中位随访时间为 9.5 年。

结论

本研究是亚洲一项大型先天性膈疝系列研究,长期随访结果表明,开腹与微创修复的复发率、复发时间或 ICU 住院中位数无显著差异,提示胸腔镜手术是一种非劣效的手术选择,与开腹修复相比可避免胃肠道并发症。

研究类型

回顾性队列研究。

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