Tyson Anna F, Sola Richard, Arnold Michael R, Cosper Graham H, Schulman Andrew M
1 Department of Surgery, Carolinas Medical Center , Charlotte, North Carolina.
2 Pediatric Surgical Associates, Levine Children's Hospital , Charlotte, North Carolina.
J Laparoendosc Adv Surg Tech A. 2017 Nov;27(11):1209-1216. doi: 10.1089/lap.2017.0298. Epub 2017 Oct 4.
Congenital diaphragmatic hernia (CDH) can be repaired open or through thoracoscopy. Thoracoscopic CDH repair could improve cosmesis and avoid the complications of laparotomy, but may have higher recurrence rates. The purpose of this study was to examine the outcomes of thoracoscopic versus open CDH repair, with regard to recurrence, perioperative parameters, and postoperative complications.
We performed a retrospective review of open versus thoracoscopic CDH repairs over an 8.5-year period. The primary outcome was hernia recurrence. Secondary outcomes included intraoperative partial pressure of carbon dioxide (pCO) levels, length of stay, and postoperative complications. All statistical analyses were performed using standard statistical methods.
A total of 54 infants underwent CDH repair during the study period, of whom 25 underwent successful thoracoscopic repair. Two patients who had undergone open repair developed recurrent diaphragmatic hernias (recurrence rate 3.7%). Operative time and intraoperative pCO levels did not differ between groups. Length of stay was shorter in the thoracoscopic cohort. Four patients in the open cohort developed ventral hernias and five developed bowel obstructions during follow-up. No long-term complications were identified in the thoracoscopic cohort. The median follow-up was 27 months.
In our experience, thoracoscopic CDH repair was performed safely and with similar outcomes compared to open repair. In addition to improved cosmesis, thoracoscopic repair may avoid some of the long-term complications of laparotomy. In our series, none of the thoracoscopic CDH repairs recurred. We conclude that thoracoscopic CDH repair is a safe and appropriate technique for select neonates.
先天性膈疝(CDH)可通过开放手术或胸腔镜手术进行修复。胸腔镜下CDH修复术可改善美观并避免开腹手术的并发症,但可能具有较高的复发率。本研究的目的是探讨胸腔镜与开放手术修复CDH在复发、围手术期参数和术后并发症方面的疗效。
我们对8.5年期间开放与胸腔镜下CDH修复术进行了回顾性研究。主要结局是疝复发。次要结局包括术中二氧化碳分压(pCO)水平、住院时间和术后并发症。所有统计分析均采用标准统计方法。
在研究期间,共有54例婴儿接受了CDH修复术,其中25例成功接受了胸腔镜修复术。2例行开放修复术的患者发生了复发性膈疝(复发率3.7%)。两组之间的手术时间和术中pCO水平无差异。胸腔镜组的住院时间较短。开放组有4例患者在随访期间发生了腹疝,5例发生了肠梗阻。胸腔镜组未发现长期并发症。中位随访时间为27个月。
根据我们的经验,胸腔镜下CDH修复术与开放修复术相比,操作安全且疗效相似。除了改善美观外,胸腔镜修复术还可避免开腹手术的一些长期并发症。在我们的系列研究中,胸腔镜下CDH修复术均未复发。我们得出结论,胸腔镜下CDH修复术是一种适用于特定新生儿的安全且合适的技术。