Yamaguchi Atsushi, Jitsuishi Tatsuya
Department of Functional Anatomy, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
Department of Functional Anatomy, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
Neurosci Res. 2024 Dec;209:9-17. doi: 10.1016/j.neures.2023.12.004. Epub 2023 Dec 30.
The precuneus is an association area in the posteromedial cortex (PMC) that is involved in high-order cognitive functions through integrating multi-modal information. Previous studies have shown that the precuneus is functionally heterogeneous and subdivided into several subfields organized by the anterior-posterior and ventral-dorsal axes. Further, the precuneus forms the structural core of brain connectivity as a rich-club hub and overlaps with the default mode network (DMN) as the functional core. This review summarizes recent research on the connectivity and cognitive functions of the precuneus. We then present our recent tractography-based studies of the precuneus and contextual these results here with respect to possible cognitive functions and resting-state networks.
楔前叶是后内侧皮质（PMC）中的一个联合区域，通过整合多模态信息参与高阶认知功能。先前的研究表明，楔前叶在功能上具有异质性，并根据前后轴和腹背轴分为几个子区域。此外，楔前叶作为一个富连接枢纽形成了脑连接的结构核心，并作为功能核心与默认模式网络（DMN）重叠。本综述总结了最近关于楔前叶连接性和认知功能的研究。然后，我们展示了我们最近基于纤维束成像的楔前叶研究，并结合可能的认知功能和静息态网络对这些结果进行了背景分析。
