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发育中的家禽对组织糖原和乳酸的处理

Tissue glycogen and lactate handling by the developing domestic fowl.

作者信息

García F J, Pons A, Alemany M, Palou A

出版信息

Comp Biochem Physiol B. 1986;85(4):727-31. doi: 10.1016/0305-0491(86)90168-9.

DOI:10.1016/0305-0491(86)90168-9
PMID:3816147
Abstract

The levels of glycogen and lactate in liver, intestine, yolk sac membrane and leg and breast muscle of domestic fowl from day 10 of "in ovo" development to day 5 after hatching compared with adults have been measured and compared with the circulating concentrations in blood of glucose and lactate. Glycogen stores in most tissues increased before hatching to attain a minimum around the eclosion and then increased to adult values in muscle and liver. Lactate maintained its plasma concentrations with higher effectiveness than plasma glucose, which increased steadily up to adult levels from hatching. The study of tissue vs plasma lactate concentration ratios suggests a general activation of lactate metabolism from hatching, coinciding with the ingestion of carbohydrate-based food. Both muscles studied, as well as intestine, seem to be net lactate producers; blood cells can speculatively be considered as lactate users and liver maintains its concentration of lactate very close to that of plasma, suggesting a fast utilization of this material as well as liver being the main site for control of circulating lactate.

摘要

对孵化后第10天至孵化后第5天的家禽肝脏、肠道、卵黄囊膜、腿部和胸部肌肉中的糖原和乳酸水平进行了测量,并与成年家禽进行了比较,同时还与血液中葡萄糖和乳酸的循环浓度进行了比较。大多数组织中的糖原储备在孵化前增加,在出雏时达到最低水平,然后在肌肉和肝脏中增加到成年水平。乳酸维持其血浆浓度的效率高于血浆葡萄糖,血浆葡萄糖从孵化后稳步增加至成年水平。对组织与血浆乳酸浓度比的研究表明,从孵化开始乳酸代谢普遍被激活,这与摄入基于碳水化合物的食物相吻合。所研究的两种肌肉以及肠道似乎都是乳酸的净生产者;血细胞可以推测为乳酸的使用者,肝脏维持其乳酸浓度与血浆非常接近,这表明该物质的快速利用以及肝脏是控制循环乳酸的主要部位。

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