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多发性骨髓瘤治疗挑战:一例椎动脉假性动脉瘤并发枕颈关节融合术的病例报告及文献综述

Multiple Myeloma Treatment Challenges: A Case Report of Vertebral Artery Pseudoaneurysm Complicating Occipitocervical Arthrodesis and a Review of the Literature.

作者信息

Reyes Soto Gervith, Ovalle Torres Carlos Salvador, Perez Terrazas Jorge, Honda Partida Kaori, Rosario Rosario Andreina, Campero Alvaro, Baldoncini Matias, Ramirez Manuel de Jesus Encarnacion, Montemurro Nicola

机构信息

Neuroscience Unit, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MEX.

Neurosurgery, National Autonomous University of Mexico (UNAM) Hospital General de Mexico, Mexico City, MEX.

出版信息

Cureus. 2023 Nov 30;15(11):e49716. doi: 10.7759/cureus.49716. eCollection 2023 Nov.

Abstract

Multiple myeloma is a hematological neoplasm that frequently affects the spinal column. Less than a fifth of this vertebral involvement corresponds to the cervical spine and cranio-cervical junction. When there is instability or neurological involvement due to compression or deformity, approaches for anterior decompression and occipitocervical stabilization are required. The correct managment of vertebral artery aneurysm associated with occipitocervical arthrodesis requires extensive knowledge of anatomy and pathology. We present a case of a vertebral pseudoaneurysm that occurred late after the resection of a C1-C2 vertebral body multiple myeloma lesion managed with endonasal endoscopic approach and posterior occipitocervical arthrodesis as well as a systematic review of the related literature. The patient recovered well, without major neurological deficits.

摘要

多发性骨髓瘤是一种常累及脊柱的血液系统肿瘤。这种椎体受累情况中,不到五分之一发生于颈椎和颅颈交界区。当因压迫或畸形导致不稳定或神经受累时,需要进行前路减压和枕颈稳定术。与枕颈融合术相关的椎动脉动脉瘤的正确处理需要对解剖学和病理学有广泛的了解。我们报告一例在采用鼻内镜入路和后路枕颈融合术治疗C1-C2椎体多发性骨髓瘤病变切除术后晚期发生的椎动脉假性动脉瘤病例,并对相关文献进行系统综述。患者恢复良好,无严重神经功能缺损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/756d/10757504/26e2d508b146/cureus-0015-00000049716-i01.jpg

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